School of Psychology and Speech Pathology, Curtin Health Innovation Research Institute, Curtin University, Perth, Australia.
J Autism Dev Disord. 2012 Dec;42(12):2693-701. doi: 10.1007/s10803-012-1526-8.
An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a single imaging scan at 18 weeks (Regular), with further scans only as indicated on clinical grounds. There was no significant difference in the rate of Autism Spectrum Disorder between the Regular (9/1,125, 0.8 %) and Intensive (7/1,167, 0.6 %) groups, nor a difference between groups in the level of autistic-like traits in early adulthood. There is no clear link between the frequency and timing of prenatal ultrasound scans and the autism phenotype.
一项现有的随机对照试验被用来研究多次超声扫描是否与自闭症表型有关。在 2834 例单胎妊娠中，随机选择 1415 例接受超声成像和连续波多普勒血流研究，在整个孕期的 5 个时间点进行（强化组），1419 例在 18 周时接受单次成像扫描（常规组），只有在临床指征的情况下才进行进一步扫描。常规组（9/1125，0.8%）和强化组（7/1167，0.6%）自闭症谱系障碍的发生率没有显著差异，两组在成年早期的自闭症样特征水平也没有差异。产前超声扫描的频率和时间与自闭症表型之间没有明确的联系。
