Department of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Catheter Cardiovasc Interv. 2013 Jan 1;81(1):97-102. doi: 10.1002/ccd.24436. Epub 2012 May 4.
Balloon angioplasty (BA) is effective in relieving neoaorta recoarctation (reCoa) after the Norwood procedure. However, recurrence is not uncommon and risk factors for success and recurrence require further elucidation. We report the results of BA for reCoa following the Norwood procedure. We examine acute results and risk factors associated with success and recurrence after BA.
Patients who underwent BA between November 2000 and June 2010 were studied. Factors for immediate success and recurrence after BA were determined using logistic regression. Recurrence-free survival was evaluated using the Kaplan-Meier curve.
Forty-seven angioplasties were performed in 39 patients. Mean age at catheterization was 5.0 ± 4.1 months. BA was successful in 40 angioplasties (85.1%). A higher preprocedure gradient across the coarctation (P = 0.04) and a higher ratio of balloon to descending aorta (P = 0.01) were associated with success. Six patients required redilation. Risk factors for recurrence included older age at Norwood (P = 0.02), younger age (P = 0.03), lower weight (P = 0.04) and smaller body surface area at balloon angioplasty (BA) (P = 0.04), and shorter duration between surgery and angioplasty (P = 0.03). Freedom from recurrence from the first catheterization was 82% after 6 months and 78% after 1 year. There were no neurologic sequelae or deaths.
BA is effective acutely and long term with limited morbidity and mortality. Recurrence occurs usually within the first year. Delay in performing the initial angioplasty may be beneficial in reducing the risk of recurrence, but further study is needed.
球囊血管成形术(BA)在缓解 Norwood 手术后的新主动脉缩窄(reCoa)方面是有效的。然而,复发并不少见,成功和复发的危险因素需要进一步阐明。我们报告了 Norwood 手术后 reCoa 的 BA 结果。我们检查了 BA 的急性结果和与 BA 后成功和复发相关的危险因素。
研究了 2000 年 11 月至 2010 年 6 月期间接受 BA 的患者。使用逻辑回归确定 BA 即刻成功和复发的因素。使用 Kaplan-Meier 曲线评估无复发生存率。
39 名患者共进行了 47 次血管成形术。导管插入时的平均年龄为 5.0 ± 4.1 个月。40 次血管成形术(85.1%)成功。缩窄处的术前梯度较高(P = 0.04)和球囊与降主动脉的比值较高(P = 0.01)与成功相关。6 名患者需要再次扩张。复发的危险因素包括 Norwood 手术时年龄较大(P = 0.02)、年龄较小(P = 0.03)、体重较轻(P = 0.04)和 BA 时体表面积较小(P = 0.04),以及手术和血管成形术之间的时间较短(P = 0.03)。从第一次导管插入后的 6 个月和 1 年,无复发率分别为 82%和 78%。没有神经后遗症或死亡。
BA 具有急性和长期的有效性,且发病率和死亡率有限。复发通常发生在第一年。延迟进行初始血管成形术可能有助于降低复发风险,但需要进一步研究。