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弥散性血管内凝血（DIC）评分：与凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）的统计学关系以及PT与APTT组合的简化评分系统

DIC Score: Statistical Relationship with PT, APTT, and Simplified Scoring Systems with Combinations of PT and APTT.

作者信息

Chandrashekar Vani

机构信息

Department of Hematology, Apollo Hospitals, 21, Greams Lane, Off Greams Road, Chennai, Tamil Nadu 600006, India.

出版信息

ISRN Hematol. 2012;2012:579420. doi: 10.5402/2012/579420. Epub 2012 Mar 5.

DOI:10.5402/2012/579420
PMID:22461997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3313579/
Abstract

We looked into the statistical association of prothrombin time (PT) and activated partial thromboplastin time (APTT) with disseminated intravascular coagulation (DIC) score calculated using the International society for thrombosis and haemostasis (ISTH) scoring system. The PT, APTT, PT + APTT, and PT/APTT ratios were evaluated against the DIC score by linear regression analysis in fifty inpatients with suspected DIC. The PT, PT + APTT, and PT/APTT ratios were all found to be statistically significant in predicting DIC scores with P values of 0.02, 0.03, and 0.02, respectively. The APTT alone was not found to be statistically significant in predicting DIC score and had a P value of 0.09. This scoring system does not need d-dimer levels and the platelet count.

摘要

我们研究了凝血酶原时间（PT）和活化部分凝血活酶时间（APTT）与使用国际血栓与止血学会（ISTH）评分系统计算的弥散性血管内凝血（DIC）评分之间的统计学关联。通过线性回归分析，对50例疑似DIC的住院患者的PT、APTT、PT + APTT以及PT/APTT比值与DIC评分进行了评估。结果发现，PT、PT + APTT以及PT/APTT比值在预测DIC评分方面均具有统计学意义，P值分别为0.02、0.03和0.02。单独的APTT在预测DIC评分方面未发现具有统计学意义，P值为0.09。该评分系统不需要D-二聚体水平和血小板计数。

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