Hamdan Abdul-Latif, Jabbour Jad, Al Zaghal Zaid, Azar Sami T
Department of Otolaryngology and Head & Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
ISRN Endocrinol. 2012;2012:208958. doi: 10.5402/2012/208958. Epub 2012 Mar 5.
The purpose of this study is to look at the prevalence of laryngopharyngeal reflux disease in patients with goiter in a group of 52 patients with goiter. All participants were asked to respond to the 9 questions on the Reflux Symptom Index (RSI). A diagnosis of LPRD based on symptoms was made for any RSI score above 10. The average score of every question was computed for all patients with goiter and compared to the corresponding average score of the controls. A P value of less than 0.05 was considered statistically significant. The total prevalence of LPRD in patients with goiter as indicated by an RSI score greater than 10 was 15.4% versus 9.1% in controls. The difference was not statistically significant (P value 0.525). Looking at the average score of the individual symptoms as listed in the RSI questionnaire, the average score of all the symptoms was higher in patients with goiter versus controls. There was no correlation between LPRD and any of the demographic variables except for nodules (P value 0.035). The presence of laryngopharyngeal symptoms in patients with goiter should alert the treating physician to the presence of laryngopharyngeal reflux disease.
本研究旨在观察52例甲状腺肿患者中喉咽反流病的患病率。所有参与者都被要求回答反流症状指数（RSI）的9个问题。对于任何RSI得分高于10的情况，基于症状做出喉咽反流病的诊断。计算所有甲状腺肿患者每个问题的平均得分，并与对照组的相应平均得分进行比较。P值小于0.05被认为具有统计学意义。RSI得分大于10表明甲状腺肿患者中喉咽反流病的总患病率为15.4%，而对照组为9.1%。差异无统计学意义（P值0.525）。查看RSI问卷中列出的各个症状的平均得分，甲状腺肿患者所有症状的平均得分高于对照组。除结节外（P值0.035），喉咽反流病与任何人口统计学变量之间均无相关性。甲状腺肿患者出现喉咽症状应提醒治疗医生注意喉咽反流病的存在。
