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Modification of sulpiride model of benign prostatic hyperplasia for evaluation of the effectiveness of drug therapy.

作者信息

Borovskaja T G, Sergeeva S A, Udut V V, Fomina T I, Jurmazov Z A, Pahomova A V, Poluektova M E, Chemerova J A, Rumpel' O A

机构信息

Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia.

出版信息

Bull Exp Biol Med. 2011 Sep;151(5):588-92. doi: 10.1007/s10517-011-1389-6.

DOI:10.1007/s10517-011-1389-6
PMID:22462052
Abstract

Specific effects of ultra-low doses of antibodies to prostate-specific antigen obtained from laboratory rats of late reproductive age with sulpiride model of benign prostatic hyperplasia were compared with the results of clinical application of the preparation. Clinical reproducibility of experimental data was proven, which suggests that the developed model is adequate for pilot testing of the effects of pharmacotherapy of this disease.

摘要

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