阿伏苯唑对全脑短暂性缺血时纹状体中神经递质氨基酸含量的影响。
Effects of afobazole on the content of neurotransmitter amino acids in the striatum in global transient ischemia.
作者信息
Baykova V S, Kadnikov I A, Voronin M V, Ganshina T S, Gnezdilova A V, Gorbunov A A, Mirzoyan P C, Seredenin S B
机构信息
V. V. Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2011 Sep;151(5):593-6. doi: 10.1007/s10517-011-1390-0.
PMID:22462053
Abstract
Anxiolytic agent afobazole (10 mg/kg intraperitoneally) 24 h after ischemia restores impaired balance of excitatory and inhibitory amino acids in the striatum of mongrel rats, normalizes their content to control levels, and activates endogenous taurine-dependent system of neuroprotection.
摘要
抗焦虑药阿伏唑（腹腔注射10毫克/千克）在缺血24小时后可恢复杂种大鼠纹状体中兴奋性和抑制性氨基酸受损的平衡，将其含量恢复至对照水平，并激活内源性牛磺酸依赖性神经保护系统。
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