Department of Neurology, Hallym University College of Medicine, Seoul, Republic of Korea.
Int J Neurosci. 2012 Aug;122(8):477-9. doi: 10.3109/00207454.2012.677883. Epub 2012 Apr 25.
Central pontine myelinolysis (CPM) is rare demyelinating disorder characterized by loss of myelin in the center of the basis pontis. The clinical features of CPM vary depending on the involved areas. Diffusion-weighted imaging (DWI) is thought to be useful for early detection during the acute phase, but its utility in this context has not been investigated thoroughly. We report the case of a CPM patient with normal initial DWI findings even at 1 week after symptom onset. To the best of our knowledge, no such cases of CPM have previously been reported.
脑桥中央髓鞘溶解症（CPM）是一种罕见的脱髓鞘疾病，其特征是脑桥基底部中心髓鞘丢失。CPM 的临床特征因受累部位而异。弥散加权成像（DWI）被认为有助于在急性期进行早期检测，但在这种情况下的效用尚未得到充分研究。我们报告了一例 CPM 患者，即使在症状出现后 1 周，初始 DWI 检查结果仍正常。据我们所知，以前没有报告过这种 CPM 病例。
