Centre de Recherche Médecine, Sciences, Santé, Santé Mentale, Société, Villejuif, France.
J Sleep Res. 2012 Oct;21(5):577-83. doi: 10.1111/j.1365-2869.2012.01015.x. Epub 2012 Mar 29.
The objective of this study was to develop a tool to help clinicians inform patients about mechanical treatment options, continuous positive airway pressure and oral appliances for obstructive sleep apnoea syndrome, and to assess its validity, reliability and acceptability. Continuous positive airway pressure is always indicated as a first-line treatment in patients with severe obstructive sleep apnoea syndrome. However, oral appliances might be an effective treatment option in patients who fail treatment attempts, and also as a first-line treatment for patients with mild to moderate obstructive sleep apnoea. To help patients choose their initial treatment, we developed an electronic decision board to present information regarding the potential benefits and side effects of the two treatment options, using the best available evidence. In 34 healthy volunteers, to test validity we evaluated the extent to which the respondents' preferences for a treatment changed predictably when the rate of effectiveness and side effects were modified. Reliability was tested by readministering the decision board 2 weeks afterwards (kappa test). The decision-board acceptability was evaluated in 99 consecutive patients newly diagnosed with obstructive sleep apnoea syndrome. We found that the decision board was valid. Reliability was excellent (κ = 0.94). Concerning acceptability, 72% of the patients were satisfied with the information provided in the decision board and 71% indicated that it helped them to make a decision. The average score of true/false test of knowledge was 7.9 of 10 (range 3-10). The decision board we developed is a valid, reliable and acceptable tool to assess patients' preferences.
本研究的目的是开发一种工具,帮助临床医生向患者介绍机械治疗选择、持续气道正压通气和口腔器具治疗阻塞性睡眠呼吸暂停综合征,并评估其有效性、可靠性和可接受性。持续气道正压通气始终被视为严重阻塞性睡眠呼吸暂停综合征患者的一线治疗方法。然而,对于治疗失败的患者,口腔器具可能是一种有效的治疗选择,也可以作为轻度至中度阻塞性睡眠呼吸暂停综合征患者的一线治疗方法。为了帮助患者选择初始治疗方法,我们开发了一个电子决策板,使用最佳可用证据,提供两种治疗方法的潜在益处和副作用的信息。在 34 名健康志愿者中,为了测试有效性,我们评估了当有效性和副作用的比率改变时,受访者对治疗的偏好是否可预测地改变。通过在两周后重新进行决策板测试(kappa 测试)来测试可靠性。在 99 名新诊断为阻塞性睡眠呼吸暂停综合征的连续患者中评估了决策板的可接受性。我们发现决策板是有效的。可靠性非常好(κ=0.94)。关于可接受性,72%的患者对决策板提供的信息感到满意,71%的患者表示它帮助他们做出了决策。知识的真/假测试的平均得分为 10 分中的 7.9 分(范围 3-10)。我们开发的决策板是一种有效、可靠和可接受的评估患者偏好的工具。