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学龄期儿童及青少年阻塞性睡眠呼吸暂停综合征患者对经鼻持续气道正压通气治疗的依从性

Adherence to nasal positive airway pressure therapy among school-aged children and adolescents with obstructive sleep apnea syndrome.

作者信息

Uong Elizabeth C, Epperson Mary, Bathon Sharon A, Jeffe Donna B

机构信息

Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63108, USA.

出版信息

Pediatrics. 2007 Nov;120(5):e1203-11. doi: 10.1542/peds.2006-2731. Epub 2007 Oct 8.

Abstract

OBJECTIVES

Although many children with obstructive sleep apnea syndrome have complete resolution of obstructive sleep apnea syndrome after adenotonsillectomy, some patients have persistent obstructive sleep apnea syndrome requiring positive airway pressure treatment. Little is known about positive airway pressure adherence among school-aged children and adolescents.

PATIENTS AND METHODS

We retrospectively reviewed records from January 2000 through December 2004 to assess positive airway pressure adherence following a comprehensive patient- and parent-focused positive airway pressure education program for children 7 to 19 years of age with persistent obstructive sleep apnea syndrome subsequent to indicated adenotonsillectomy. A polysomnogram was obtained before and after initiation of positive airway pressure therapy. Adherence was defined as > 4 hours per night and > or = 5 nights per week of positive airway pressure use. Clock-counter meters determined hours per night and nights per week of positive airway pressure use; parents estimated hours per night of positive airway pressure use. Nonparametric tests assessed associations between adherence and various clinical parameters and symptoms.

RESULTS

Forty-six patients (56% male; 39% black, 61% white; mean age: 13.6 years; mean BMI: 39.8 kg/m2) were included. Two refused positive airway pressure. Meter readings were available for 27 patients (59%); positive airway pressure was used, on average, 7.0 hours per night, 73% of the week, and for a mean of 18.1 months. Nineteen (70%) were adherent regardless of age. There was good agreement between parental report and meter readings. Patients with greater improvement in apnea-hypopnea index were more likely to be adherent. Clinical parameters and symptoms improved after positive airway pressure therapy regardless of age or adherence.

CONCLUSIONS

In this retrospective study, positive airway pressure adherence and symptom improvement among school-aged children and adolescents was achieved with comprehensive patient and parent education and follow-up.

摘要

目的

尽管许多阻塞性睡眠呼吸暂停综合征患儿在腺样体扁桃体切除术后阻塞性睡眠呼吸暂停综合征完全缓解,但一些患者仍有持续性阻塞性睡眠呼吸暂停综合征,需要进行气道正压治疗。对于学龄儿童和青少年的气道正压治疗依从性了解甚少。

患者与方法

我们回顾性分析了2000年1月至2004年12月的记录,以评估在一项针对7至19岁腺样体扁桃体切除术后持续性阻塞性睡眠呼吸暂停综合征患儿及其家长的全面气道正压教育计划后气道正压治疗的依从性。在开始气道正压治疗前后进行了多导睡眠图检查。依从性定义为每晚使用气道正压治疗>4小时且每周使用>或=5晚。时钟计数器测量每晚使用气道正压治疗的小时数和每周使用的天数;家长估计每晚使用气道正压治疗的小时数。非参数检验评估依从性与各种临床参数和症状之间的关联。

结果

纳入46例患者(56%为男性;39%为黑人,61%为白人;平均年龄:13.6岁;平均BMI:39.8kg/m²)。2例拒绝气道正压治疗。27例患者(59%)有测量读数;气道正压治疗平均每晚使用7.0小时,每周使用73%的天数,平均使用18.1个月。19例(70%)无论年龄大小均依从。家长报告与测量读数之间有良好的一致性。呼吸暂停低通气指数改善较大者更可能依从。无论年龄或依从性如何,气道正压治疗后临床参数和症状均有改善。

结论

在这项回顾性研究中,通过全面的患者和家长教育及随访,学龄儿童和青少年实现了气道正压治疗的依从性和症状改善。

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