Basker Mona M, Russell Paul Swamidhas Sudhakar, Russell Sushila, Moses Prabhakar D
Department of Psychiatry, Child and Adolescent Psychiatry Unit, Christian Medical College, Vellore, Tamil Nadu, India.
Indian J Med Sci. 2010 Feb;64(2):72-80.
Adolescent depression needs to be identified and treated in the primary care settings. There is no clinician-rated measure validated in India for identifying depression among adolescents.
We studied the diagnostic accuracy, reliability, and validity of Children's Depression Rating Scale - Revised (CDRS-R) for primary care pediatrics.
Prospective study in three schools in Southern India.
Adolescents recruited were administered the CDRS-R by a pediatrician and clinical psychologist along with Beck Depression Inventory (BDI) for convergent validity. Impact of Event Scale (IES) for divergent validity and the ICD-10 clinical diagnosis of depressive disorders using modified Kiddie-SADS-Present and Lifetime Version (K-SADS-PL) interview as reference standard were administered by a psychiatrist independently. Appropriate statistical analyses for diagnostic accuracy, reliability, and validity were done.
A cut-off score of 30 (sensitivity = 83%, specificity = 84%; AUC in ROC = 87%) in CDRS-R is suggested for diagnosing depression. The inter-rater reliability (r = 0.73) and test-retest reliability (r = 0.98) was good. In addition to the adequate face and content validity, CDRS-R had good internal consistency (α = 0.76), high convergent (r = 0.71; P = 0.001), and divergent validity (r = 0.28; P = 0.20). There was moderate concordance with the reference standard of ICD-10 diagnosis (45.5%) in identifying depression and CDRS-R discriminated 80% of the other psychiatric morbidity. The six-factor structure explained 60.6% of variance.
The CDRS-R showed strong psychometric properties and is now available for use in the primary-care pediatric practice in India.
青少年抑郁症需要在初级保健机构中得到识别和治疗。在印度,尚无经过验证的临床医生评定量表可用于识别青少年抑郁症。
我们研究了儿童抑郁评定量表修订版(CDRS-R)在初级保健儿科中的诊断准确性、可靠性和有效性。
在印度南部三所学校进行的前瞻性研究。
招募的青少年由一名儿科医生和一名临床心理学家进行CDRS-R评定,同时使用贝克抑郁量表(BDI)进行聚合效度评估。使用事件影响量表(IES)进行区分效度评估,由一名精神科医生独立使用改良的儿童版情感障碍及精神分裂症问卷现状与终生版(K-SADS-PL)访谈作为参考标准对抑郁障碍进行ICD-10临床诊断。对诊断准确性、可靠性和有效性进行了适当的统计分析。
建议CDRS-R的临界值为30(敏感性=83%,特异性=84%;ROC曲线下面积=87%)用于诊断抑郁症。评定者间信度(r = 0.73)和重测信度(r = 0.98)良好。除了具有足够的表面效度和内容效度外,CDRS-R还具有良好的内部一致性(α = 0.76)、高聚合效度(r = 0.71;P = 0.001)和区分效度(r = 0.28;P = 0.20)。在识别抑郁症方面,与ICD-10诊断参考标准的一致性为中等(45.5%),CDRS-R能够区分80%的其他精神疾病。六因素结构解释了6方差的60.6%。
CDRS-R显示出强大的心理测量学特性,现在可用于印度的初级保健儿科实践。