Child and Adolescent Psychiatry Unit, Christian Medical College, Vellore 632 004, India.
Indian J Pediatr. 2012 Jan;79 Suppl 1:S45-51. doi: 10.1007/s12098-011-0438-5. Epub 2011 May 28.
To compare the diagnostic accuracy of a self-rated and a clinician rated measure of depression for primary care use in school setting by pediatricians.
Two tools for screening depression were administered to early adolescents in three schools. These included the self-rated Beck Depression Inventory (BDI), pediatrician rated Children's Depression Rating Scale-Revised (CDRS-R), and ICD-10 clinical interview by a psychiatrist as reference standard. These tools were compared for their overall performance using Areas Under the Curve (AUC) of Receiver Operating Characteristic (ROC) curves. The optimal screening threshold score for both tools were identified from their sensitivity and specificity plotted for all threshold scores. For the optimal cut-off scores, the diagnostic accuracy parameters like sensitivity, specificity, predictive values, likelihood ratio and diagnostic odds ratio were calculated using contingency table.
The area under the curve for BDI was 0.67 and CDRS was 0.50 suggesting that BDI as a screening tool has better diagnostic accuracy. The optimal screening threshold score for BDI was 18 with a sensitivity of 63 and specificity of 70. For the CDRS-R cut-off score of 59, the sensitivity was 36 and specificity was 82 respectively. Using both tools concurrently improved the diagnostic accuracy.
Using the ROC characteristics and various validity indices, the authors showed that BDI has better sensitivity and CDRS-R a better specificity. It might be prudent to use both these instrument simultaneously to improve the identification of depression in primary care settings like school health clinic.
比较自我评估和临床医生评估的抑郁量表在儿科医生对学校环境中的初级保健使用中的诊断准确性。
对三所学校的早期青少年进行了两种抑郁筛查工具的评估。这些工具包括自我评估贝克抑郁量表(BDI)、儿科医生评估儿童抑郁评定量表修订版(CDRS-R),以及由精神科医生进行的 ICD-10 临床访谈作为参考标准。使用接受者操作特征(ROC)曲线的曲线下面积(AUC)比较这些工具的整体性能。从所有阈值分数的敏感性和特异性绘制图中确定这两种工具的最佳筛查阈值分数。对于最佳截断分数,使用列联表计算诊断准确性参数,如敏感性、特异性、预测值、似然比和诊断比值比。
BDI 的曲线下面积为 0.67,CDRS 为 0.50,表明 BDI 作为筛查工具具有更好的诊断准确性。BDI 的最佳筛查阈值分数为 18,敏感性为 63,特异性为 70。对于 CDRS-R 的截断分数 59,敏感性为 36,特异性为 82。同时使用这两种工具可以提高诊断准确性。
使用 ROC 特征和各种有效性指标,作者表明 BDI 具有更好的敏感性,而 CDRS-R 具有更好的特异性。在学校卫生诊所等初级保健环境中,同时使用这两种工具可能更明智,可以提高抑郁的识别率。