Patrizi Annalisa, Medri Matelda, Raone Beatrice, Bianchi Federica, Aprile Sylvia, Neri Iria
Section of Dermatology, Department of Internal Medicine, Aging and Nephrologic Diseases, University of Bologna, Bologna, Italy.
Pediatr Dermatol. 2012 Sep-Oct;29(5):571-4. doi: 10.1111/j.1525-1470.2012.01734.x. Epub 2012 Apr 4.
We performed a retrospective study covering a 10-year period (January 1997-January 2007) on children referred to our unit or followed up for Becker's nevus (BN). The aim of this study was to better define the characteristics of BN in childhood, when this hypermelanosis is more frequent than the limited number of studies might suggest. Our data show that BN in children has predilection sites similar to those in adults, but hypertrichosis is rarer. Sun exposure does not appear to play an etiopathogenetic role. The higher incidence in men reported in adult case studies was not found in children. During and after puberty, androgenic stimulation is known to play a pathogenetic role in BN, especially in men, but our cases were mostly younger than 6 years old.
我们进行了一项回顾性研究,涵盖了10年期间(1997年1月至2007年1月)转诊至我们科室或接受贝克痣(BN)随访的儿童。本研究的目的是更好地界定儿童期BN的特征,因为这种色素沉着过度在儿童期比现有数量有限的研究所显示的更为常见。我们的数据表明,儿童BN的好发部位与成人相似,但多毛症较少见。阳光照射似乎不发挥病因学作用。成人病例研究中报道的男性发病率较高在儿童中未发现。在青春期期间及之后,已知雄激素刺激在BN发病中起作用,尤其是在男性中,但我们的病例大多年龄小于6岁。