Hang'ombe Mudenda B, Mwansa James C L, Muwowo Sergio, Mulenga Phillip, Kapina Muzala, Musenga Eric, Squarre David, Mataa Liywali, Thomas Suzuki Y, Ogawa Hirohito, Sawa Hirofumi, Higashi Hideaki
University of Zambia, School of Veterinary Medicine, PO Box 32379, Lusaka, Zambia.
Trop Doct. 2012 Jul;42(3):136-9. doi: 10.1258/td.2012.110454. Epub 2012 Apr 3.
There has been a reduction of incidences of anthrax in the developed countries but it is still a public health problem in the developing countries where communities live in interface areas with wildlife. An outbreak of anthrax in Hippopotamus amphibious was observed in Zambia. Following the death of hippopotamuses, suspected human cases were reported. The objective of this study was to isolate and confirm Bacillus anthracis and to determine the antimicrobial susceptibility for the management of the disease. Of the specimens collected, 29.4% (95% confidence interval [CI], 11.4-56.0) were from humans, 42.1% (95% CI, 21.1-66.0) were from hippopotamuses and 20.0% (95% CI, 6.61-44.3) from the soil were found to be positive were for B. anthracis. An antimicrobial susceptibility test revealed that all the isolates were found to be sensitive to the recommended antibiotics. The disease control was achieved by case management and by explaining to the communities that they should avoid contact with animals that die from unknown causes.
发达国家炭疽发病率有所下降,但在发展中国家,尤其是那些社区与野生动物栖息地接壤的地区,炭疽仍是一个公共卫生问题。赞比亚曾出现过一起河马感染炭疽的疫情。河马死亡后,出现了疑似人类感染病例。本研究的目的是分离并确认炭疽芽孢杆菌,并确定其药敏情况,以便对该病进行治疗。在采集的样本中,29.4%(95%置信区间[CI],11.4 - 56.0)来自人类,42.1%(95% CI,21.1 - 66.0)来自河马,20.0%(95% CI,6.61 - 44.3)来自土壤,这些样本被检测出炭疽芽孢杆菌呈阳性。药敏试验显示,所有分离株对推荐使用的抗生素均敏感。通过病例管理以及向社区宣传应避免接触死因不明的动物,实现了对该病的控制。