Pace V, Artico M, Ciccariello M, Bonanni G
Istituto di Fisiologia Generale, Università degli Studi La Sapienza di Roma.
Minerva Dietol Gastroenterol. 1990 Apr-Jun;36(2):63-75.
The authors, keeping in mind their clinical, diagnostic and therapeutic experience on ulcerous gastric and duodenal pathology, underline the effectiveness of the traditional antacids as well as that of the modern up-to-date antisecretory and cytoprotective agents. After having put into evidence the causes that can provoke peptic ulcer not excluding that of iatrogenic and their probable aetiopathogenetic mechanism and having hinted at another pathology that uses the same therapeutic remedies, the gastro-oesophagus reflux, they discuss in detail the active principles used in the gastric or duodenal pathology, the possible side and/or secondary effects that in the long run are determined when using only the modern therapy with the usual antacids. Therefore, they hope that these therapies are used after carefully considering the general clinical and anatomicopathologic situation of the lesion that must be created.
作者们牢记其在胃溃疡和十二指肠溃疡病理方面的临床、诊断和治疗经验，强调了传统抗酸剂以及现代最新的抗分泌和细胞保护剂的有效性。在阐述了可能引发消化性溃疡的原因（不排除医源性原因）及其可能的发病机制，并提及了另一种使用相同治疗方法的病理情况——胃食管反流后，他们详细讨论了用于治疗胃或十二指肠疾病的活性成分，以及仅使用现代常规抗酸剂治疗时可能长期产生的副作用和/或继发效应。因此，他们希望在仔细考虑病变的总体临床和解剖病理情况后再使用这些疗法。
