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[消化性溃疡发病机制中的环境危险因素。香烟烟雾的作用]

[Environmental risk factors in the pathogenesis of peptic ulcer. The role of cigarette smoke].

作者信息

Sablich R, Benedetti G, Serraino D

机构信息

Servizio di Gastroenterologia ed Endoscopia Digestiva, U.S.L. n. 11, Pordenonese, S.O.S. Maria degli Angeli, Pordenone.

出版信息

Minerva Dietol Gastroenterol. 1990 Apr-Jun;36(2):99-103.

PMID:2247267
Abstract

Smoking habit has been evaluated in 108 patients with gastric or duodenal ulcer diagnosed by endoscopy and in a control group of 147 endoscopically normal subjects. We found a positive association for both the gastric and duodenal ulcer (relative risk of 3.5). Furthermore, an increasing risk was associated both with the duration of smoking and with the amount of cigarettes smoked daily. Conversely, no significant association was demonstrated between peptic ulcer and the more os less precocious age at starting smoking or with the nicotine and tar content of the cigarettes usually smoked. Among ex-smokers, an increasing risk (relative risk of 2.0) was observed for gastric ulcer only.

摘要

对108例经内镜诊断为胃或十二指肠溃疡的患者以及147例内镜检查正常的对照组受试者的吸烟习惯进行了评估。我们发现胃溃疡和十二指肠溃疡均存在正相关(相对风险为3.5)。此外,吸烟时间和每日吸烟量均与风险增加有关。相反,消化性溃疡与开始吸烟时的年龄大小或通常所吸香烟的尼古丁和焦油含量之间未显示出显著关联。在已戒烟者中,仅观察到胃溃疡风险增加(相对风险为2.0)。

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