Department of Surgery, Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Cold Spring Harb Perspect Med. 2012 Apr;2(4):a006445. doi: 10.1101/cshperspect.a006445.
The blood and lymphatic systems are the two major circulatory systems in our body. Although the blood system has been studied extensively, the lymphatic system has received much less scientific and medical attention because of its elusive morphology and mysterious pathophysiology. However, a series of landmark discoveries made in the past decade has begun to change the previous misconception of the lymphatic system to be secondary to the more essential blood vascular system. In this article, we review the current understanding of the development and pathology of the lymphatic system. We hope to convince readers that the lymphatic system is no less essential than the blood circulatory system for human health and well-being.
血液和淋巴系统是人体的两大循环系统。尽管血液系统已经得到了广泛的研究，但由于其难以捉摸的形态和神秘的病理生理学，淋巴系统受到的科学和医学关注要少得多。然而，过去十年中的一系列里程碑式的发现开始改变以前的误解，即认为淋巴系统是次要的，不如更重要的血液血管系统。在本文中，我们回顾了对淋巴系统发育和病理学的现有认识。我们希望让读者相信，淋巴系统对于人类的健康和福祉与血液循环系统同样重要。
