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0.05%丙酸氯倍他索喷雾剂用于治疗中度至重度斑块状银屑病。

Clobetasol propionate spray 0.05% for the treatment of moderate to severe plaque psoriasis.

作者信息

Menter Alan

机构信息

Baylor Psoriasis Research Center, Baylor Research Institute, Baylor University Medical Center, 3900 Junius St, Ste 145, Dallas, TX 75246, USA.

出版信息

Cutis. 2012 Feb;89(2):89-94.

PMID:22474733
Abstract

Clobetasol propionate is a super-high potent class 1 topical corticosteroid available in several formulations, including a spray formulation that is approved for use up to 4 weeks in patients aged 18 years and older with moderate to severe plaque psoriasis. The efficacy and safety of clobetasol propionate spray 0.05% has been extensively evaluated in clinical trials in more than 2200 patients with moderate to severe plaque psoriasis. This article reviews the efficacy, safety, and tolerability of clobetasol propionate spray 0.05%. Clobetasol propionate spray 0.05% is a topical product with a documented efficacy and safety profile with good acceptability in patients with moderate to severe plaque psoriasis.

摘要

丙酸氯倍他索是一种超强效的1类外用皮质类固醇,有多种剂型,包括一种喷雾剂型,已获批用于18岁及以上中度至重度斑块状银屑病患者,最长使用4周。0.05%丙酸氯倍他索喷雾剂的疗效和安全性已在超过2200例中度至重度斑块状银屑病患者的临床试验中得到广泛评估。本文综述了0.05%丙酸氯倍他索喷雾剂的疗效、安全性和耐受性。0.05%丙酸氯倍他索喷雾剂是一种外用产品,在中度至重度斑块状银屑病患者中具有已证实的疗效和安全性,且耐受性良好。

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