[良性前列腺增生症患者组织学前列腺炎与前列腺特异性抗原、前列腺体积、前列腺特异抗原密度、国际前列腺症状评分、最大尿流率及残余尿量的相关性]

[Correlation of histological prostatitis with PSA, prostate volume, PSAD, IPSS, Qmax and PVR in BPH patients].

作者信息

Zhang Hong-Tuan, Xu Yong, Chang Ji-Wu, Zhang Zhi-Hong, Liu Ran-Lu, Ma Bao-Jie

机构信息

Department of Urology and Andrology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China.

出版信息

Zhonghua Nan Ke Xue. 2012 Mar;18(3):208-11.

PMID:22474983

Abstract

OBJECTIVE

To explore the correlation of histologically proven prostatitis with the level of prostate specific antigen (PSA), prostate volume, PSA density (PSAD), international prostate symptom score (IPSS), maximum flow rate (Qmax) and post-void residual volume (PVR) in men with symptoms of benign prostate hyperplasia (BPH).

METHODS

Totally 673 patients surgically treated for BPH were divided into Groups A and B in accordance with histological findings, the former including those with histological prostatitis, and the latter without it. Comparisons were made between the two groups in the PSA level, prostate volume, PSAD, IPSS, Qmax and PVR.

RESULTS

The PSA level, prostate volume, IPSS and PVR were significantly higher in Group A ([5.64 +/- 2.48] microg/L, [43.66 +/- 13.11] ml, 24.72 +/- 5.39 and [124.90 +/- 49.80] ml) than in B ([4.97 +/- 1.99] microg/L, [40.41 +/- 11.44] ml, 23.40 +/- 6.21 and [112.73 +/- 50.03] ml) (P<0.05), while Qmax markedly lower in the former ([6.94 +/- 3.23] ml/s) than in the latter ([7.75 +/- 3.52] ml/s) (P<0.05), but PSAD showed no statistically significant difference between the two groups (0.129 +/- 0.048 vs 0.123 +/- 0.034, P>0.05).

CONCLUSION

Histological prostatitis can significantly increase the PSA level, prostate volume, IPSS and PVR, and reduce the Qmax of the patient, but is not correlated with PSAD. It is an important factor influencing the clinical progression of BPH.

摘要

目的

探讨经组织学证实的前列腺炎与良性前列腺增生（BPH）症状男性的前列腺特异性抗原（PSA）水平、前列腺体积、PSA密度（PSAD）、国际前列腺症状评分（IPSS）、最大尿流率（Qmax）及残余尿量（PVR）之间的相关性。

方法

将673例接受BPH手术治疗的患者根据组织学检查结果分为A组和B组，A组为有组织学前列腺炎的患者，B组为无组织学前列腺炎的患者。比较两组患者的PSA水平、前列腺体积、PSAD、IPSS、Qmax及PVR。

结果

A组患者的PSA水平、前列腺体积、IPSS及PVR显著高于B组（分别为[5.64±2.48]μg/L、[43.66±13.11]ml、24.72±5.39及[124.90±49.80]ml，B组分别为[4.97±1.99]μg/L、[40.41±11.44]ml、23.40±6.21及[112.73±50.03]ml）（P<0.05），而A组患者的Qmax显著低于B组（分别为[6.94±3.23]ml/s和[7.75±3.52]ml/s）（P<0.05），但两组患者的PSAD差异无统计学意义（分别为0.129±0.048和0.123±0.034，P>0.05）。