Division of Nuclear Medicine, Department of Radiology, Keck School of Medicine University of Southern California, Los Angeles, CA 90033, USA.
Clin Nucl Med. 2012 May;37(5):e110-6. doi: 10.1097/RLU.0b013e31824c81ee.
Sodium fluoride (NaF) is a bone-seeking positron-emitting tracer with high sensitivity and specificity for detection of osseous lesions, particularly osteolytic lesions. We believe that NaF positron emission tomography (PET)/computed tomography (CT) scans can provide a more thorough and conclusive evaluation of bone diseases than conventional Technetium-99m-methylene diphosphonate bone scans. Understanding both normal and pathologic patterns is important for the evaluation and interpretation of these studies. Thus, an atlas of NaF positron emission tomography/computed tomography bone scans demonstrating benign, pathologic, and malignant osseous lesions as well as extraosseous lesions will be invaluable in the correct interpretation and diagnosis of osseous lesions.
氟化钠(NaF)是一种亲骨性正电子发射示踪剂,具有高灵敏度和特异性,可用于检测骨病变,特别是溶骨性病变。我们认为,氟化钠正电子发射断层扫描(PET)/计算机断层扫描(CT)扫描可以比传统的锝-99m-亚甲基二膦酸盐骨扫描更全面、更具结论性地评估骨疾病。了解正常和病理模式对于评估和解释这些研究非常重要。因此,一本氟化钠正电子发射断层扫描/计算机断层扫描骨扫描图谱,展示良性、病理性和恶性骨病变以及骨外病变,对于正确解读和诊断骨病变将非常有价值。