Rotman B, Eber B, Dusleag J, Brussee H, Weinrauch V, Klein W
Medizinischen Universitätsklinik Graz.
Wien Med Wochenschr. 1990 Sep 15;140(17):448-51.
By signal averaging it is possible to registrate late, fragmented low amplitude signals (late potentials, LP's) from the bodysurface 26 patients (21 males, 5 females) with a mean age of 57 years were investigated by signal averaging, Holter-monitoring and cardiac catheterization. 11 patients had a dilative cardiomyopathy (group A), 10 patients a coronary heart disease (group B), 5 of them with an ejection fraction greater than 50%, 5 of them with a reduced ejection fraction, whereas the control-group with 5 patients (group C) showed no coronary stenosis or reduced ventricular function, 6 out of 11 patients with dilative cardiomyopathy showed LP's; all of these with Lown IVb had LP's. In 2 patients with coronary heart disease and good left ventricular function late potentials were found, and in all 5 patients with disturbed left ventricular function. The control-group revealed no late potentials although 4 patients had Lown IVa or more in Holter-ECG. In conclusion, late potentials show a good correlation to malignant ventricular ectopic beats in patients with dilative cardiomyopathy and coronary heart disease, especially when the left ventricular function is reduced.
通过信号平均技术,可以记录来自体表的晚期、碎裂的低振幅信号(晚期电位,LP)。对26例患者(21例男性,5例女性)进行了研究,平均年龄57岁,采用信号平均技术、动态心电图监测和心脏导管检查。11例患者患有扩张型心肌病(A组),10例患者患有冠心病(B组),其中5例射血分数大于50%,5例射血分数降低,而5例患者的对照组(C组)未显示冠状动脉狭窄或心室功能降低。11例扩张型心肌病患者中有6例显示晚期电位;所有这些Lown IVb级患者均有晚期电位。在2例冠心病且左心室功能良好的患者中发现了晚期电位,在所有5例左心室功能受损的患者中也发现了晚期电位。对照组未显示晚期电位,尽管4例患者在动态心电图中有Lown IVa或更高分级。总之,晚期电位与扩张型心肌病和冠心病患者的恶性室性早搏有良好的相关性,尤其是当左心室功能降低时。