Histopathologic analysis of bladder in patient with cloacal exstrophy.

We report the case of a newborn infant with cloacal exstrophy. On the 16th day after birth, complete primary exstrophy repair was performed. The bladder tissue obtained during surgery contained collagen tissue and a little smooth muscle, as well as a few neuron cells and kit-positive interstitial cells in the submucosal layer. This is the first report of a histopathologic analysis of the bladder tissue in cloacal exstrophy. We also discuss the influence of the pathologic changes on bladder dysfunction.