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N-乙酰半胱氨酸治疗人体砷中毒

N-acetylcysteine in the treatment of human arsenic poisoning.

作者信息

Martin D S, Willis S E, Cline D M

机构信息

Department of Family Medicine, East Carolina University, School of Medicine, Greenville, NC.

出版信息

J Am Board Fam Pract. 1990 Oct-Dec;3(4):293-6.

PMID:2248097
Abstract

A 32-year-old man was brought to the emergency department 5 1/2 hours after ingesting a potentially lethal dose (900 mg) of sodium arsenate ant poison in a suicide attempt. The patient deteriorated progressively for 27 hours. After intramuscular dimercaprol and supportive measures failed to improve his condition, he was given N-acetylcysteine intravenously. The patient showed remarkable clinical improvement during the following 24 hours and was discharged from the hospital several days later.

摘要

一名32岁男子在企图自杀时摄入了可能致命剂量(900毫克)的砷酸钠杀虫剂,5个半小时后被送往急诊室。该患者病情持续恶化了27小时。在肌肉注射二巯丙醇和采取支持措施均未能改善其病情后,给他静脉注射了N-乙酰半胱氨酸。在接下来的24小时内,患者的临床症状有显著改善,几天后出院。

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