Department of Dermatology, Charité Medical University, Berlin, Germany.
G Ital Dermatol Venereol. 2012 Apr;147(2):171-8.
In vivo reflectance confocal microscopy (RCM) is a non-invasive diagnostic technique that offers the evaluation of the skin at real time with cellular resolution. In the past decade, multiple studies have been performed showing the clinical applicability of RCM for the diagnosis of melanoma and non melanoma skin cancer (NMSC). In this regard, RCM has moved from a research tool to a valuable diagnostic technique being applied in daily clinical practice. In this regard, RCM aids in the diagnosis and differential diagnosis of various skin diseases and may also be used for selection of the biopsy site. Furthermore, RCM allows monitoring of a skin lesion over time without tissue alteration and thus represents a valuable method for treatment monitoring.
体内反射共聚焦显微镜（RCM）是一种非侵入性的诊断技术，可实时提供细胞分辨率的皮肤评估。在过去的十年中，已经进行了多项研究，表明 RCM 可用于诊断黑色素瘤和非黑色素瘤皮肤癌（NMSC），具有临床适用性。在这方面，RCM 已从研究工具转变为一种有价值的诊断技术，应用于日常临床实践中。在这方面，RCM 有助于诊断和鉴别诊断各种皮肤病，也可用于选择活检部位。此外，RCM 允许在不改变组织的情况下随时间监测皮肤病变，因此是一种有价值的治疗监测方法。
