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放射/放射外科并发症及治疗失败的管理

Management of radiation/radiosurgical complications and failures.

作者信息

Roche Pierre-Hugues, Noudel Rémy, Régis Jean

机构信息

Service de neurochirurgie, CHU Nord, Chemin des Bourrely, 13915, Marseille Cedex 20, France.

出版信息

Otolaryngol Clin North Am. 2012 Apr;45(2):367-74, ix. doi: 10.1016/j.otc.2011.12.007. Epub 2012 Feb 11.

Abstract

To describe the incidence and the course of complications after the radiosurgical treatment of vestibular schwannomas, the authors reviewed their own experience and reviewed the literature. Failure is described in less than 3% of cases, and this had to be distinguished from transient enlargement of tumor volume. In case of failure, microsurgical resection or another radiosurgical procedure should be discussed. The risk of radio-induced tumorigenesis is not clearly established with single-dose radiosurgical technique. Incidence and management of potential complications should be explained at the time of decision making in the management of vestibular schwannomas.

摘要

为描述前庭神经鞘瘤放射外科治疗后并发症的发生率及病程,作者回顾了自身经验并查阅了文献。不到3%的病例出现治疗失败情况,且必须将其与肿瘤体积的短暂增大相区分。若出现治疗失败,应讨论进行显微手术切除或再次进行放射外科手术。单剂量放射外科技术导致放射性肿瘤发生的风险尚不明确。在决定治疗前庭神经鞘瘤时,应说明潜在并发症的发生率及处理方法。

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