输尿管移行细胞癌的手术方式与临床病理特征的相关性。
Correlation between surgical modality and clinicopathologic characteristics for ureteral transitional cell carcinoma.
机构信息
Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
出版信息
Clin Transl Oncol. 2012 Apr;14(4):312-6. doi: 10.1007/s12094-012-0800-8.
PURPOSE
To investigate the relationship between surgical modality and clinicopathologic features for ureteral transitional cell carcinoma.
METHODS
The correlation between surgical modality and clinicopathology characteristics of 146 patients with ureteral carcinoma having undergone surgery was evaluated using univariate analysis by a general linear model.
RESULTS
43.8%, 51.4% and 4.8% of patients experienced nephroureterectomy, renal conservation management and palliative operations, respectively, with a mean survival time of 97.3, 101.3 and 51.0 months (p=0.069) accordingly. Univariate analysis by general linear model indicated that the size of lesions, pathologic stage and tumour grade had a statistically significant impact on surgical modality (p=0.000, p=0.001 and p=0.017, respectively).
CONCLUSION
Tumour stage and grade, as well as tumour size, correlate with surgical modality.
目的
探讨手术方式与输尿管移行细胞癌临床病理特征之间的关系。
方法
采用一般线性模型的单因素分析，评估 146 例接受手术治疗的输尿管癌患者的手术方式与临床病理特征之间的相关性。
结果
43.8%、51.4%和 4.8%的患者分别接受了肾输尿管切除术、保肾治疗和姑息性手术，平均生存时间分别为 97.3、101.3 和 51.0 个月（p=0.069）。一般线性模型的单因素分析表明，病变大小、病理分期和肿瘤分级对手术方式有统计学显著影响（p=0.000、p=0.001 和 p=0.017）。
结论
肿瘤分期和分级以及肿瘤大小与手术方式相关。
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