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输尿管移行细胞癌的手术方式与临床病理特征的相关性。

Correlation between surgical modality and clinicopathologic characteristics for ureteral transitional cell carcinoma.

机构信息

Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

出版信息

Clin Transl Oncol. 2012 Apr;14(4):312-6. doi: 10.1007/s12094-012-0800-8.

DOI:10.1007/s12094-012-0800-8
PMID:22484639
Abstract

PURPOSE

To investigate the relationship between surgical modality and clinicopathologic features for ureteral transitional cell carcinoma.

METHODS

The correlation between surgical modality and clinicopathology characteristics of 146 patients with ureteral carcinoma having undergone surgery was evaluated using univariate analysis by a general linear model.

RESULTS

43.8%, 51.4% and 4.8% of patients experienced nephroureterectomy, renal conservation management and palliative operations, respectively, with a mean survival time of 97.3, 101.3 and 51.0 months (p=0.069) accordingly. Univariate analysis by general linear model indicated that the size of lesions, pathologic stage and tumour grade had a statistically significant impact on surgical modality (p=0.000, p=0.001 and p=0.017, respectively).

CONCLUSION

Tumour stage and grade, as well as tumour size, correlate with surgical modality.

摘要

目的

探讨手术方式与输尿管移行细胞癌临床病理特征之间的关系。

方法

采用一般线性模型的单因素分析,评估 146 例接受手术治疗的输尿管癌患者的手术方式与临床病理特征之间的相关性。

结果

43.8%、51.4%和 4.8%的患者分别接受了肾输尿管切除术、保肾治疗和姑息性手术,平均生存时间分别为 97.3、101.3 和 51.0 个月(p=0.069)。一般线性模型的单因素分析表明,病变大小、病理分期和肿瘤分级对手术方式有统计学显著影响(p=0.000、p=0.001 和 p=0.017)。

结论

肿瘤分期和分级以及肿瘤大小与手术方式相关。

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本文引用的文献

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Upper urinary tract transitional cell carcinoma. A 10-year experience.上尿路移行细胞癌。十年经验总结。
Tumori. 2008 Jan-Feb;94(1):75-8. doi: 10.1177/030089160809400114.
2
Outcomes of surgical treatment for upper urinary tract transitional cell carcinoma: comparison of retroperitoneoscopic and open nephroureterectomy.上尿路移行细胞癌的外科治疗结果:后腹腔镜与开放性肾输尿管切除术的比较
World J Surg Oncol. 2008 Jan 15;6:3. doi: 10.1186/1477-7819-6-3.
3
Oncologic outcomes of extravesical stapling of distal ureter in laparoscopic nephroureterectomy.
腹腔镜肾输尿管切除术中输尿管远端膀胱外吻合的肿瘤学结局
J Endourol. 2007 Sep;21(9):1025-7. doi: 10.1089/end.2006.0306.
4
Endoscopic ureteral procedures for one-step nephroureterectomy: experience in 100 cases.用于一期肾输尿管切除术的内镜输尿管手术:100例经验
J Endourol. 2007 Sep;21(9):1019-24. doi: 10.1089/end.2006.0426.
5
Endourologic management of patients with upper-tract transitional-cell carcinoma: long-term follow-up in a single center.上尿路移行细胞癌患者的腔内泌尿外科治疗:单中心长期随访
J Endourol. 2007 Sep;21(9):1005-9. doi: 10.1089/end.2006.9922.
6
Elective management of transitional cell carcinoma of the distal ureter: can kidney-sparing surgery be advised?远端输尿管移行细胞癌的选择性治疗:能否建议保留肾手术?
BJU Int. 2007 Aug;100(2):264-8. doi: 10.1111/j.1464-410X.2007.06993.x. Epub 2007 May 26.
7
Comparison of open nephroureterectomy and ureteroscopic and percutaneous management of upper urinary tract transitional cell carcinoma.开放性肾输尿管切除术与输尿管镜及经皮治疗上尿路移行细胞癌的比较。
Urology. 2006 Jun;67(6):1181-7. doi: 10.1016/j.urology.2005.12.034.
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Factors affecting the survival of patients treated by standard nephroureterectomy for transitional cell carcinoma of the upper urinary tract.影响接受标准肾输尿管切除术治疗的上尿路移行细胞癌患者生存的因素。
Int Urol Nephrol. 2006;38(1):9-13. doi: 10.1007/s11255-005-3151-3.
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Percutaneous therapy of low stage and grade urothelial neoplasia: long-term follow up.低分期和低分级尿路上皮肿瘤的经皮治疗:长期随访
Arch Ital Urol Androl. 2005 Dec;77(4):211-4.
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