炎症性肠病和肠道白塞病中的模仿与欺骗
Mimicry and deception in inflammatory bowel disease and intestinal behçet disease.
作者信息
Grigg Erika L, Kane Sunanda, Katz Seymour
机构信息
Dr. Grigg is a Gastroenterology Fellow at Georgia Health Sciences University in Augusta, Georgia. Dr. Kane is a Professor of Medicine in the Division of Gastroenterology and Hepatology at the Mayo Clinic in Rochester, Minnesota. Dr. Katz is a Clinical Professor of Medicine at Albert Einstein College of Medicine in Great Neck, New York.
出版信息
Gastroenterol Hepatol (N Y). 2012 Feb;8(2):103-12.
Behçet disease (BD) is a rare, chronic, multisystemic, inflammatory disease characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Intestinal BD occurs in 10-15% of BD patients and shares many clinical characteristics with inflammatory bowel disease (IBD), making differentiation of the 2 diseases very difficult and occasionally impossible. The diagnosis of intestinal BD is based on clinical findings-as there is no pathognomonic laboratory test-and should be considered in patients who present with abdominal pain, diarrhea, weight loss, and rectal bleeding and who are susceptible to intestinal BD. Treatment for intestinal BD is similar to that for IBD, but overall prognosis is worse for intestinal BD. Although intestinal BD is extremely rare in the United States, physicians will increasingly encounter these challenging patients in the future due to increased immigration rates of Asian and Mediterranean populations.
白塞病（BD）是一种罕见的慢性多系统炎症性疾病，其特征为复发性口腔溃疡、生殖器溃疡、葡萄膜炎和皮肤病变。肠道白塞病发生于10%至15%的白塞病患者中，与炎症性肠病（IBD）有许多临床特征相同，这使得两种疾病的鉴别非常困难，有时甚至无法鉴别。肠道白塞病的诊断基于临床发现——因为没有特异性的实验室检查——对于出现腹痛、腹泻、体重减轻和直肠出血且易患肠道白塞病的患者应予以考虑。肠道白塞病的治疗与炎症性肠病相似，但肠道白塞病的总体预后更差。尽管在美国肠道白塞病极为罕见，但由于亚洲和地中海人群移民率的增加，医生在未来将越来越多地遇到这些具有挑战性的患者。
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