Gynecological Clinic, Rigshospitalet University Hospital, University of Copenhagen, Copenhagen, Denmark.
Acta Obstet Gynecol Scand. 2012 Jul;91(7):810-5. doi: 10.1111/j.1600-0412.2012.01416.x. Epub 2012 May 15.
Oral contraceptives (OC) are the most popular contraception in Denmark. Overall figures on use are well described, but more detailed use patterns according to type and age need to be updated.
To assess trends in the use of OC including progestogen-only pills among Danish women in 1998-2010 and to describe in detail use patterns in 2010. Design. Annual cross-sectional prescription statistics.
Denmark.
Danish women 10-49 years old.
Analysis of prescription data from the National Registry of Medicinal Products Statistics from 1 January 1998 through 31 December 2010.
Combined OC (COC) with 50 μg estrogen decreased their market share from 3% in 1998 to zero in 2010, and COC with 30-40 μg estrogen decreased to 50% in 2010, in contrast, COC with 20 μg estrogen increased to 46% in 2010. Progestogen-only pills accounted for 4%. COC with levonorgestrel decreased, while the use of pills with desogestrel and gestodene among two-thirds of current users was constant.
Low-dose COCs gradually replaced middle-dose pills. Pills with newer progestogens are used primarily by young women, and 85% of users in 2010 were on products with desogestrel, gestodene, drospirenone or cyproteroneacetate. We still need low-dose pills with 1(st) and 2(nd) generation progestogens on the Scandinavian market.
口服避孕药(OC)是丹麦最受欢迎的避孕方法。总体使用数据描述得很好,但需要更新更详细的按类型和年龄划分的使用模式。
评估丹麦妇女在 1998 年至 2010 年期间使用 OC(包括单纯孕激素避孕药)的趋势,并详细描述 2010 年的使用模式。
年度横断面处方统计。
丹麦。
10-49 岁的丹麦妇女。
对 1998 年 1 月 1 日至 2010 年 12 月 31 日期间国家药品统计登记处的处方数据进行分析。
含 50μg 雌激素的复方 OC(COC)市场份额从 1998 年的 3%降至 2010 年的 0%,而含 30-40μg 雌激素的 COC 则降至 2010 年的 50%,相比之下,含 20μg 雌激素的 COC 则增至 2010 年的 46%。单纯孕激素避孕药占 4%。含左炔诺孕酮的 COC 减少,而目前使用者中有三分之二使用的是去氧孕烯和孕二烯酮避孕药。
低剂量 COC 逐渐取代中剂量药丸。含有新型孕激素的药丸主要被年轻妇女使用,2010 年 85%的使用者使用的是含去氧孕烯、孕二烯酮、屈螺酮或醋酸环丙孕酮的产品。我们仍需要在斯堪的纳维亚市场上使用含有第一代和第二代孕激素的低剂量药丸。