Department of Burns and Plastic Surgery, First Affiliated Hospital of General Hospital of Chinese People's Liberation Army, Beijing 100048, China.
Chin Med J (Engl). 2012 Mar;125(5):951-3.
Varicella is a self-limited disease, but sometimes it may be associated with some serious life-threatening complications.Necrotizing fasciitis is a rare complication of varicella. This is a case of a 7-year-old girl with septic shock caused by necrotizing fasciitis as a complication of varicella. Swelling and pain in the left inguinal region and left axillary region were found five days after varicella. Then a high fever occurred followed by hypotension. Fluid infusion, vasopressor and antibiotics were administered. Group A beta-hemolytic Streptococcus was isolated from exudates from the wounds. The clinical symptoms markedly improved after surgical drainage and removal of the necrotic tissue. Both wounds were covered with skin grafts after healthy granulation tissue formed. Although there have been few reports of life-threatening necrotizing fasciitis following varicella in western countries, it is rare in China. Usually patients with varicella were admitted to pediatric or infectious disease department but not surgical departments; so that the clinicians should be aware that varicella may be complicated by life-threatening surgical infections. Necrotizing fasciitis should be suspected in patients of varicella who showed an increasing pain and swelling in any body areas associated with increasing fever and local erythema. Early identification, surgical drainage and debridement are essential for successful treatment of necrotizing fasciitis.
水痘是一种自限性疾病,但有时它可能与一些严重的危及生命的并发症有关。坏死性筋膜炎是水痘的罕见并发症。这是一例 7 岁女孩因坏死性筋膜炎并发水痘而导致感染性休克的病例。在出现水痘后 5 天,发现左侧腹股沟区和左腋窝区肿胀和疼痛。随后出现高热,继而出现低血压。给予补液、血管加压药和抗生素治疗。从伤口渗出物中分离出 A 组β溶血性链球菌。在进行手术引流和清除坏死组织后,临床症状明显改善。当健康肉芽组织形成后,两个伤口均覆盖了皮肤移植物。虽然在西方国家有少数关于水痘后发生危及生命的坏死性筋膜炎的报道,但在中国却很少见。通常,患有水痘的患者会被收治在儿科或传染病科,而不是外科科室;因此,临床医生应该意识到水痘可能会并发危及生命的外科感染。对于出现任何部位疼痛和肿胀加剧、伴有发热和局部红斑的水痘患者,应怀疑坏死性筋膜炎。早期识别、手术引流和清创是成功治疗坏死性筋膜炎的关键。