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[第四脑室出口梗阻的内镜治疗]

[Endoscopic treatment for fourth ventricular outlet obstruction].

作者信息

Hu Zhi-qiang, Guan Feng, Huang Hui, Zhu Guang-tong, Mao Bei-bei, Wang Shao-heng, Kang Zhuang

机构信息

Department of Neurosurgery, Affiliated Shijitan Hospital, Capital Medical University, Beijing 100038, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2012 Jan 17;92(3):184-7.

Abstract

OBJECTIVE

To explore the therapeutic efficacies of endoscope for fourth ventricular outlet obstruction (FVOO).

METHODS

Endoscopic third ventriculostomy (ETV) was performed for 30 cases. The circumstances of third ventricular floor and basal cistern were observed and recorded intra-operatively. Meanwhile the fourth ventricular exploration and fistulation were performed across enlarged aqueduct. And the velocity and flow rate of aqueduct, fourth ventricular outlet and stoma were evaluated post-operatively with Cine-MR (magnetic resonance).

RESULTS

Standard ETV was performed successfully in 28 patients. Fourth ventricular exploration (n = 6) and outlet membrane fistulation (n = 2) were carried out. The mean follow-up period was 2.3 years (range: 0.5 - 4.0). The overall success rate was 78.6%.

CONCLUSION

ETV is a viable therapeutic option for FVOO patients. The therapeutic effects of outlet membrane fistulation require further observations.

摘要

目的

探讨内镜治疗第四脑室出口梗阻(FVOO)的疗效。

方法

对30例患者实施内镜下第三脑室造瘘术(ETV)。术中观察并记录第三脑室底部及基底池情况。同时,经扩大的导水管进行第四脑室探查及造瘘。术后采用电影磁共振成像(Cine-MR)评估导水管、第四脑室出口及造瘘口的流速和流量。

结果

28例患者成功实施标准ETV。进行了第四脑室探查(n = 6)和出口膜造瘘(n = 2)。平均随访时间为2.3年(范围:0.5 - 4.0年)。总成功率为78.6%。

结论

ETV是FVOO患者可行的治疗选择。出口膜造瘘的治疗效果有待进一步观察。

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