Suppr超能文献

经颈静脉肝内门体分流术联合栓塞治疗食管胃静脉曲张:38例报告

[Transjugular intrahepatic portosystemic shunt plus embolotherapy in the treatment of gastroesophageal varices: a report of 38 patients].

作者信息

Wang Hong-bo, Zhang An-zhong, Yang Chong-mei, Cui Yi, Zhang Jun-yong, Liu Fu-li, Zhang Chun-qing

机构信息

Department of Gastroenterology, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China. Email:

出版信息

Zhonghua Yi Xue Za Zhi. 2012 Feb 14;92(6):411-3.

Abstract

OBJECTIVE

To evaluate the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) plus embolotherapy in the treatment of patients with gastroesophageal varices.

METHODS

A total of 36 patients with gastroesophageal varices underwent the therapies of TIPS plus embolotherapy from July 2005 to March 2011 at Provincial Hospital Affiliated to Shandong University. The rechecked items included abdominal ultrasound examination, liver function test and blood routine examination at Day 7 post-operation. All received endoscopic examinations at Month 1.

RESULTS

The technical success rate of TIPS plus embolotherapy was 100%. The portal vein pressures declined from (28 ± 8) mm Hg (1 mm Hg = 0.133 kPa) to (14 ± 7) mm Hg at post-operation. Angiography showed gastroesophageal varices disappeared in all patients. Both liver function and gastroesophageal varices markedly improved. During the follow-up period of 3 - 6 months, 4 cases had hepatic encephalopathy and 1 case stent restenosis at post-operation. And most cases were resolved after treatment. No rebleeding occurred during the follow-up period.

CONCLUSIONS

The combined modality of TIPS plus embolotherapy can effectively lower portal vein pressure and cure esophageal and gastric varice bleeding. As a safe and excellent interventional procedure with fewer complications and a lower recurrence rate of portal hypertension, it has great clinical values in the treatment of portal hypertension and gastroesophageal varices.

摘要

目的

评估经颈静脉肝内门体分流术(TIPS)联合栓塞疗法治疗胃食管静脉曲张患者的疗效。

方法

2005年7月至2011年3月,山东大学附属省立医院共有36例胃食管静脉曲张患者接受了TIPS联合栓塞疗法。复查项目包括术后第7天的腹部超声检查、肝功能检查和血常规检查。所有患者在术后1个月均接受了内镜检查。

结果

TIPS联合栓塞疗法的技术成功率为100%。术后门静脉压力从(28±8)mmHg(1mmHg = 0.133kPa)降至(14±7)mmHg。血管造影显示所有患者的胃食管静脉曲张均消失。肝功能和胃食管静脉曲张均明显改善。在3至6个月的随访期内,4例患者术后发生肝性脑病,1例患者出现支架再狭窄。大多数病例经治疗后得到缓解。随访期间无再出血发生。

结论

TIPS联合栓塞疗法可有效降低门静脉压力,治愈食管和胃静脉曲张出血。作为一种安全、优良的介入手术,并发症少,门静脉高压复发率低,在门静脉高压和胃食管静脉曲张的治疗中具有重要的临床价值。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验