Department of Surgery, Denver Health Medical Center and The University of Colorado Denver, Colorado 80204, USA.
J Trauma Acute Care Surg. 2012 Mar;72(3):796-8. doi: 10.1097/TA.0b013e318243da8c.
Penetrating cardiac injuries necessitate rapid resuscitation and repair, most commonly with the use of pledgeted sutures. Hemostasis can be difficult to obtain with injuries near coronary vessels or with friable tissue that does not hold suture. We describe the use of BioGlue, a synthetic bovine albumin and glutaraldehyde mix, as a hemostatic adjunct in these challenging cases.
Patients sustaining penetrating cardiac injury undergoing emergent operation from January 2000 to January 2010 were reviewed.
During the 10-year study period, 67 patients required emergent operation for a cardiac injury, with three patients undergoing BioGlue repair of their ventricle. All patients were male with a mean age of 40 years ± 8 years. In two patients, BioGlue was used in addition to suture repair to control hemorrhage, while in one patient BioGlue was used as the only cardiac repair. Hemostasis was achieved in all cases, and there were no cardiac complications in 20 months (range 15-26 months) of follow-up.
To our knowledge, this is the first description of the use of BioGlue for repair of penetrating cardiac injuries. This technique should be added to the armamentarium in managing complex cardiac wounds.
III.
穿透性心脏损伤需要迅速复苏和修复，最常使用带垫片缝线。靠近冠状动脉或组织脆弱无法固定缝线的损伤，止血可能很困难。我们描述了使用生物胶（一种合成牛白蛋白和戊二醛混合物）作为这些具有挑战性病例的止血辅助剂。
回顾了 2000 年 1 月至 2010 年 1 月期间因穿透性心脏损伤而紧急手术的患者。
在 10 年的研究期间，67 名患者因心脏损伤需要紧急手术，其中 3 名患者接受了生物胶修复心室。所有患者均为男性，平均年龄为 40 岁±8 岁。在 2 例患者中，生物胶与缝线修复一起用于控制出血，而在 1 例患者中，生物胶是唯一的心脏修复方法。所有病例均实现止血，在 20 个月（15-26 个月）的随访中无心脏并发症。
据我们所知，这是首次描述使用生物胶修复穿透性心脏损伤。该技术应添加到处理复杂心脏伤口的工具中。
III。
