全球流行的大肠杆菌 ST131 分离株的特征（1991 年至 2010 年）。
Characterization of globally spread Escherichia coli ST131 isolates (1991 to 2010).
机构信息
REQUIMTE, Faculdade Farmácia Universidade Porto, Porto, Portugal.
出版信息
Antimicrob Agents Chemother. 2012 Jul;56(7):3973-6. doi: 10.1128/AAC.00475-12. Epub 2012 Apr 9.
Abstract
The characterization of a broad representative sample of ST131 Escherichia coli isolates from different origins and settings (1991 to 2010) revealed that this clonal group has likely diversified recently and that the expansion of particular variants has probably been favored by the capture of diverse, multidrug-resistant IncFII plasmids (pC15-1a, pEK499, pKF3-140-like). The low ability to adhere and to grow as biofilm that was detected in this study suggests unknown mechanisms for the persistence of this clonal group which need to be further explored.
摘要
对来自不同来源和环境的广泛代表性 ST131 大肠杆菌分离株（1991 年至 2010 年）进行的特征描述表明，这个克隆群可能是最近多样化的，而特定变体的扩展可能是由于捕获了不同的、多药耐药的 IncFII 质粒（pC15-1a、pEK499、pKF3-140 样）而得到了促进。本研究中检测到的这种克隆群的粘附和生物膜生长能力较低，表明其持续存在的未知机制需要进一步探索。
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