Milchgrub S, McMurry N K, Vuitch F, Dorfman H D
Department of Pathology, University of Texas, Southwestern Medical Center, Dallas 75235-9072.
Cancer. 1990 Dec 15;66(12):2636-41. doi: 10.1002/1097-0142(19901215)66:12<2636::aid-cncr2820661228>3.0.co;2-3.
The clinical and pathologic features of four cases of benign mesenchymoma in which mature cartilage represented the predominant component are reported. The distinctive histologic feature in all four cases was a lobular proliferation of cartilaginous tissue exhibiting a spectrum of hyaline cartilage, fibrocartilage, myxoid cartilage, and cartilage with ossification and even bone marrow formation, intimately associated with mature adipose tissue and vascular elements. The localization of these tumors was in the proximity of a bone, but not attached to the periosteum or in continuity with a joint. Because these lesions may be mistaken for other cartilaginous neoplasms of soft tissue, recognition of this entity has potentially important diagnostic and therapeutic implications in that mutilating surgery may be avoided.
本文报告了4例以成熟软骨为主要成分的良性间叶瘤的临床及病理特征。所有4例的独特组织学特征为小叶状增生的软骨组织，呈现出透明软骨、纤维软骨、黏液样软骨以及伴有骨化甚至骨髓形成的软骨的一系列表现，与成熟脂肪组织和血管成分密切相关。这些肿瘤位于骨附近，但不附着于骨膜或与关节连续。由于这些病变可能被误诊为其他软组织软骨肿瘤，认识这一实体在避免致残性手术方面具有潜在的重要诊断和治疗意义。
