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避免青光眼导致的视力丧失:这是不可避免的吗?

Avoidable sight loss from glaucoma: is it unavoidable?

机构信息

NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust, UCL Institute of Ophthalmology, London, UK.

出版信息

Br J Ophthalmol. 2012 Jun;96(6):816-20. doi: 10.1136/bjophthalmol-2012-301499. Epub 2012 Apr 4.

Abstract

AIMS

To review the characteristics of patients attending a tertiary ophthalmic referral centre certified as sight impaired (SI) or severely sight impaired (SSI) from glaucoma.

METHODS

One hundred consecutive patients certified SI/SSI from the Glaucoma Service at Moorfields Eye Hospital, London, from January 2007 were identified from the England and Wales certification of visual impairment database. Clinical and demographic data were collected from hospital case records.

RESULTS

The median (IQR) age of patients at presentation was 66.3 (55.6 to 75.3) years; median (IQR) interval to certification was 62.2 (22.5 to 129.3) months. Fifty-seven patients presented with bilateral SSI (median (IQR) age 70.4 (59.0 to 76.9) years); interval to certification was 35.4 (5.6 to 78.1) months. Seventeen patients presented with a bilateral SI (median (IQR) age 62.1 (58.7 to 68.4) years; median (IQR) interval to certification: 137.4 (64.4 to 190.4) months). Twenty-eight patients showed disease progression while under National Health Service hospital eye service care, five of whom had no certifiable visual impairment in either eye at presentation. This was attributed to inadequate intraocular pressure control; five of these patients (18%) were deemed poorly compliant to topical hypotensive medication.

CONCLUSIONS

Over 80% patients on the certification of visual impairment register from Moorfields Eye Hospital with glaucoma as the primary cause had a significant visual disability at presentation, with almost two-thirds of patients presenting bilaterally 'blind'. There appear to be delays to certification. Despite being under the hospital eye service, a number of glaucoma patients still progress to certifiable visual impairment.

摘要

目的

回顾在一家获得认证的眼科转诊中心就诊的视力受损(SI)或严重视力受损(SSI)的青光眼患者的特征。

方法

从伦敦 Moorfields 眼科医院的青光眼服务中,从 2007 年 1 月开始,从英格兰和威尔士的视力障碍认证数据库中确定了 100 名连续获得 SI/SSI 认证的患者。从医院病历中收集了临床和人口统计学数据。

结果

患者就诊时的中位(IQR)年龄为 66.3(55.6 至 75.3)岁;中位(IQR)认证间隔时间为 62.2(22.5 至 129.3)个月。57 名患者表现为双侧 SSI(中位(IQR)年龄 70.4(59.0 至 76.9)岁);认证间隔时间为 35.4(5.6 至 78.1)个月。17 名患者表现为双侧 SI(中位(IQR)年龄 62.1(58.7 至 68.4)岁;中位(IQR)认证间隔时间:137.4(64.4 至 190.4)个月)。28 名患者在接受国民保健服务医院眼科服务治疗期间出现疾病进展,其中 5 名患者在就诊时双眼均无可认证的视力障碍。这归因于眼内压控制不足;其中 5 名患者(18%)被认为对局部降压药物的依从性差。

结论

在 Moorfields 眼科医院接受视力障碍认证的患者中,超过 80%的青光眼患者在就诊时已经存在严重的视力障碍,其中近三分之二的患者双眼失明。认证似乎存在延迟。尽管在医院眼科服务范围内,一些青光眼患者仍会进展到可认证的视力障碍。

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