Kakizaki Aya, Fujimura Taku, Numata Ikuko, Hashimoto Akira, Aiba Setsuya
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Case Rep Dermatol. 2012 Jan;4(1):27-30. doi: 10.1159/000336207. Epub 2012 Jan 30.
Pseudolymphomatous folliculitis (PLF), which sometimes mimicks cutaneous lymphoma, is a rare manifestation of cutaneous pseudolymphoma and cutaneous lymphoid hyperplasia. We describe a 57-year-old Japanese woman with PLF on the nose that resembled cutaneous lymphoma clinically. The biopsy specimen revealed dense lymphocytes, especially CD1a+ cells, infiltrated around the hair follicles. Without any additional treatment, her nodule rapidly decreased before we performed a second biopsy for analysis of the clonal gene rearrangement. Though PLF typically behaves as benign lymphohyperplasia, differentiation from cutaneous lymphoma is necessary.
假淋巴瘤性毛囊炎（PLF）有时会模仿皮肤淋巴瘤，是皮肤假淋巴瘤和皮肤淋巴样增生的一种罕见表现。我们描述了一名57岁的日本女性，其鼻部患有PLF，临床上类似皮肤淋巴瘤。活检标本显示毛囊周围有密集的淋巴细胞浸润，尤其是CD1a+细胞。在我们进行第二次活检以分析克隆基因重排之前，未经任何额外治疗，她的结节迅速缩小。尽管PLF通常表现为良性淋巴增生，但仍有必要与皮肤淋巴瘤相鉴别。
