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鼻部假淋巴瘤性毛囊炎

Pseudolymphomatous folliculitis on the nose.

作者信息

Kakizaki Aya, Fujimura Taku, Numata Ikuko, Hashimoto Akira, Aiba Setsuya

机构信息

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

出版信息

Case Rep Dermatol. 2012 Jan;4(1):27-30. doi: 10.1159/000336207. Epub 2012 Jan 30.

Abstract

Pseudolymphomatous folliculitis (PLF), which sometimes mimicks cutaneous lymphoma, is a rare manifestation of cutaneous pseudolymphoma and cutaneous lymphoid hyperplasia. We describe a 57-year-old Japanese woman with PLF on the nose that resembled cutaneous lymphoma clinically. The biopsy specimen revealed dense lymphocytes, especially CD1a+ cells, infiltrated around the hair follicles. Without any additional treatment, her nodule rapidly decreased before we performed a second biopsy for analysis of the clonal gene rearrangement. Though PLF typically behaves as benign lymphohyperplasia, differentiation from cutaneous lymphoma is necessary.

摘要

假淋巴瘤性毛囊炎(PLF)有时会模仿皮肤淋巴瘤,是皮肤假淋巴瘤和皮肤淋巴样增生的一种罕见表现。我们描述了一名57岁的日本女性,其鼻部患有PLF,临床上类似皮肤淋巴瘤。活检标本显示毛囊周围有密集的淋巴细胞浸润,尤其是CD1a+细胞。在我们进行第二次活检以分析克隆基因重排之前,未经任何额外治疗,她的结节迅速缩小。尽管PLF通常表现为良性淋巴增生,但仍有必要与皮肤淋巴瘤相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178e/3322626/3929b5859f19/cde-0004-0027-g01.jpg

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