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Acquired epidermolysis bullosa. A bullous disease associated with autoimmunity to type VII (anchoring fibril) collagen.

作者信息

Woodley D T, Briggaman R A, Gammon W R

机构信息

Department of Dermatology, Stanford University, California.

出版信息

Dermatol Clin. 1990 Oct;8(4):717-26.

PMID:2249362
Abstract

Epidermolysis bullosa acquisita (EBA) is a chronic subepidermal blistering disease of the skin in which one finds tissue-bound and circulating antibodies are bound to type VII collagen. Although not definitely proven, current evidence strongly suggests that EBA is an autoimmune disease. The true etiology or initiating event that triggers EBA has not been identified.

摘要

相似文献

1
Acquired epidermolysis bullosa. A bullous disease associated with autoimmunity to type VII (anchoring fibril) collagen.
Dermatol Clin. 1990 Oct;8(4):717-26.
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Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid.大疱性类天疱疮和获得性大疱性表皮松解症患者的自身抗体诱导真皮-表皮分离需要粒细胞衍生的弹性蛋白酶和明胶酶B。
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