Acquired epidermolysis bullosa. A bullous disease associated with autoimmunity to type VII (anchoring fibril) collagen.

Epidermolysis bullosa acquisita (EBA) is a chronic subepidermal blistering disease of the skin in which one finds tissue-bound and circulating antibodies are bound to type VII collagen. Although not definitely proven, current evidence strongly suggests that EBA is an autoimmune disease. The true etiology or initiating event that triggers EBA has not been identified.