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巩膜隧道感染的临床微生物学特征和治疗结果。

Clinicomicrobiological characteristics and treatment outcome of sclerocorneal tunnel infection.

机构信息

Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, India.

出版信息

Cornea. 2012 Jul;31(7):780-5. doi: 10.1097/ICO.0b013e3182254b62.

Abstract

PURPOSE

To analyze the clinical presentation, microbiological evaluation, and management of post-cataract surgery sclerocorneal tunnel infection.

METHODS

This is a retrospective chart review of 11 patients with sclerocorneal tunnel infection after cataract surgery, managed between November 2006 and October 2009. The clinical characteristics and treatment outcomes were analyzed.

RESULTS

All patients presented within 1 to 10 weeks of primary surgery. The presenting visual acuity ranged from hand motions to 20/50. Ten of 11 patients had sclerocorneal involvement, and 4 patients had associated endophthalmitis. The causative organisms were fungus (n = 6), bacteria (n = 4), or both (n = 1). Deroofing of the tunnel and sclerocorneal patch graft was done in 4 patients. Intensive medication was administered to all patients. The final visual acuity ranged from light perception to 20/50 at a mean follow-up of 119 days (median, 66 days; range, 2-357 days). Five patients had ≥20/100 vision. The mean interval between presentation to resolution of infiltrate and formation of peripheral scarring was 20 days (median, 11 days; range, 2-66 days).

CONCLUSIONS

Sclerocorneal tunnel infection must be microbiologically evaluated. Intensive medical management, wound revision and repair may lead to a favorable outcome.

摘要

目的

分析白内障术后巩膜隧道感染的临床特征、微生物学评估和处理方法。

方法

这是一项对 2006 年 11 月至 2009 年 10 月期间收治的 11 例白内障术后巩膜隧道感染患者的回顾性病历分析。分析了其临床特征和治疗结果。

结果

所有患者均在初次手术后 1 周至 10 周内出现症状。初诊时的视力从手动视力到 20/50 不等。11 例患者中有 10 例出现巩膜角膜受累,4 例伴有眼内炎。致病病原体包括真菌(6 例)、细菌(4 例)或两者混合(1 例)。4 例患者行隧道去顶和巩膜角膜移植片移植。所有患者均接受强化药物治疗。平均随访 119 天(中位数 66 天;范围 2-357 天)后,最终视力从光感至 20/50 不等。5 例患者视力≥20/100。浸润消退和周边瘢痕形成的平均间隔为 20 天(中位数 11 天;范围 2-66 天)。

结论

巩膜隧道感染必须进行微生物学评估。强化药物治疗、手术修复可能会获得良好的预后。

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