Soda Tetsuji, Yamanaka Kazuaki, Hirai Toshiaki, Kishikawa Hidefumi, Nishimura Kenji, Ichikawa Yasuji
The Department of Urology, Hyogo Prefectural Nishinomiya Hospital, Japan.
Hinyokika Kiyo. 2012 Mar;58(3):177-80.
A 67-year-old man had pain and swelling in the bilateral inguinal region. His past medical history included non-alcoholic steatohepatitis and liver cirrhosis. A clinical examination revealed a solid mass that was palpable along with the bilateral spermatic cord from the external inguinal ring to the root of the scrotum. Other than a hydrocele in the right testis, the epididymis and testes were intact. Abdominal computed tomography showed ascites and a solid tumor of the bilateral spermatic cord. Magnetic resonance imaging findings did not suggest malignancy, while antibiotics showed no effects. The patient wanted relief from the inguinal pain and a bilateral high orchiectomy was performed, during which time the spermatic cord was found firmly adhered to the surrounding tissue, and could not be completely resected. A histopathological examination showed epithelial mesothelioma. For additional examination of the ascites, the patient underwent paracentesis, which revealed an extremely high level of hyaluronic acid. Our working diagnosis was peritoneal malignant mesothelioma that had infiltrated the bilateral spermatic cord. We began systemic chemotherapy treatment with pemetrexed and cisplatin, but, the patient died 3 months after the operation.
一名67岁男性双侧腹股沟区疼痛、肿胀。他既往有非酒精性脂肪性肝炎和肝硬化病史。临床检查发现,从腹股沟外环至阴囊根部可触及双侧精索走行区的实性肿物。除右侧睾丸鞘膜积液外,附睾和睾丸均完整。腹部计算机断层扫描显示腹水及双侧精索实性肿瘤。磁共振成像结果不提示恶性肿瘤,抗生素治疗无效。患者希望缓解腹股沟疼痛,遂行双侧高位睾丸切除术,术中发现精索与周围组织紧密粘连,无法完全切除。组织病理学检查显示为上皮样间皮瘤。为进一步检查腹水,患者接受了腹腔穿刺术,结果显示透明质酸水平极高。我们初步诊断为腹膜恶性间皮瘤侵犯双侧精索。我们开始用培美曲塞和顺铂进行全身化疗,但患者术后3个月死亡。