Humphreys Mitchell R, Castle Erik P, Andrews Paul E
Department of Urology, Mayo Clinic Arizona, Phoenix, AZ 85054, USA.
Arch Esp Urol. 2012 Apr;65(3):407-14.
Minimally invasive surgery is advancing to new frontiers that attempt to limit patient morbidities while providing excellent surgical outcomes. At the forefront of these efforts is natural orifice surgery, where surgical incisions can theoretically be eliminated. The purpose of this report is to describe the evolution of the clinical development of the natural orifice translumenal endoscopic radical prostatectomy (NOTES RP). It details the early experimental cadaver and animal work and the many challenges encountered to bring this procedure to clinical fruition. While the procedure remains in its infancy the clinical application to human patients shows its potential merit to positively impact the surgical control of prostate cancer. Early clinical experience does not allow the ability to draw definitive conclusions about the procedure at this time but the potential benefits for a new minimally invasive inexpensive treatment for prostate cancer patients is promising.
微创手术正在迈向新的前沿领域，旨在在提供出色手术效果的同时，尽量减少患者的发病几率。这些努力的前沿是自然腔道手术，理论上可以消除手术切口。本报告的目的是描述经自然腔道内镜下根治性前列腺切除术（NOTES RP）临床发展的演变过程。它详细介绍了早期的尸体实验和动物实验工作，以及将该手术应用于临床所遇到的诸多挑战。虽然该手术仍处于起步阶段，但在人类患者中的临床应用显示出其对前列腺癌手术控制产生积极影响的潜在价值。目前的早期临床经验尚无法就该手术得出明确结论，但作为一种新的微创且低成本的前列腺癌治疗方法，其潜在益处前景广阔。
