Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Surg Oncol. 2012 Nov;106(6):753-6. doi: 10.1002/jso.23121. Epub 2012 Apr 11.
This study examined the surgical outcome of non-curative resection in elderly patients with gastric cancer.
The study reviewed 278 patients who underwent non-curative resection for advanced gastric cancer. The clinicopathological features of elderly patients (≥ 75 years, n = 257) and younger patients (<75 years, n = 21) were compared.
Although no difference was observed in terms of preoperative performance, there were distinct differences in terms of albumin level, presence of symptoms, and the rate of comorbidities between the two groups. The postoperative morbidity and mortality rate did not differ between the two groups. Age, preoperative performance status, preoperative transfusion, and presence of comorbidity were not independent predictors of postoperative complications. However, the extent of gastric resection and combined resection were closely related to postoperative complications in patients with non-curative gastrectomy.
In a setting of non-curative resection for gastric cancer, age was not a limiting factor. Rather, the risk of postoperative morbidity should be considered carefully in total gastrectomy and combined resection.
本研究旨在探讨老年胃癌患者非治愈性切除的手术效果。
本研究回顾了 278 例接受晚期胃癌非治愈性切除术的患者。比较了老年患者（≥75 岁，n=257）和年轻患者（<75 岁，n=21）的临床病理特征。
尽管两组患者术前的一般情况无明显差异，但白蛋白水平、症状存在与否以及合并症发生率存在明显差异。两组患者的术后并发症发生率和死亡率无差异。年龄、术前一般情况、术前输血和合并症均不是术后并发症的独立预测因素。然而，对于非治愈性胃切除患者，胃切除范围和联合切除与术后并发症密切相关。
在非治愈性胃癌切除的情况下，年龄不是限制因素。相反，在全胃切除和联合切除时应仔细考虑术后并发症的风险。
