Li J X
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1990 May;12(3):206-9.
Thirty-one cases of midline peripheral T-cell lymphoma (MPTL), treated during the past two years in our hospital, are reported. All were proven by immunohistochemical stain on frozen section, using a panel of antibodies: IIIC4 (CD5), Leu-2, Leu-3, Leu-4, T,p55, T11, Ia, Ki-1, IL2-R, B1/DAKO-CD22, Kappa, Lambda and IgM. Three cases were also stained with LCA, UCHL-1, MT1, MT2, MB1 and MB2 monoclonal antibodies in paraffin sections, and the results conformed with the frozen-sectionmethod. According to our present and previous reports, it is worthy of note that most of the so-called midline malignant reticuloses (MMR) in the past, including necrotic granulomatosis and malignant granulomatosis, are actually MPTL. In view of MPTL being highly malignant and not very rare in this country, it is emphasized that this disease should be paid more attention and recognized anew. More active treatment should be given to improve the results.
本文报告了我院在过去两年中治疗的31例中线外周T细胞淋巴瘤（MPTL）。所有病例均经冰冻切片免疫组织化学染色证实，所用抗体组合包括：IIIC4（CD5）、Leu-2、Leu-3、Leu-4、T、p55、T11、Ia、Ki-1、IL2-R、B1/DAKO-CD22、κ、λ和IgM。3例还在石蜡切片中用LCA、UCHL-1、MT1、MT2、MB1和MB2单克隆抗体进行了染色，结果与冰冻切片法一致。根据我们目前和以前的报告，值得注意的是，过去大多数所谓的中线恶性网状细胞增多症（MMR），包括坏死性肉芽肿病和恶性肉芽肿病，实际上都是MPTL。鉴于MPTL在我国具有高度恶性且并非十分罕见，强调应更加重视并重新认识这种疾病。应给予更积极的治疗以改善治疗效果。
