Shen E J
Beijing Tiantan Hospital.
Zhonghua Zhong Liu Za Zhi. 1990 May;12(3):210-2.
Twelve cases of lung cancer with brain metastasis, which comprised 20% of all lung cancer patients complicated with brain metastasis in the same period in our hospital, underwent resection of both lung and brain lesions. There were 9 men and 3 women. The ages ranged from 29 to 65. The site of metastasis was supratentorial in 11 patients and on the right side in 8. The interval between thoracotomy and craniotomy was 18 days-5 years. There was no operative death. Six patients have survived for more than one year. Surgical approach to lung cancer with brain metastasis has proved to be better in comparison with other methods of treatment. Obviously, adjuvant therapy after surgery may play an important role in improving survival. Whether craniotomy or thoracotomy is first performed depends on the presence or absence of life-threatening neurological symptoms. If the patient's condition allows, the second operation should be performed as soon as possible. It is emphasized that in lung cancer patients, pre- and postoperative routine CT scan of the brain should be regularly done for early detection of brain metastasis. Meanwhile, a timely, planned, staged operation may improve survival.
12例肺癌脑转移患者接受了肺和脑病变切除术,占同期我院所有合并脑转移肺癌患者的20%。其中男性9例,女性3例。年龄范围为29至65岁。转移部位位于幕上的有11例,位于右侧的有8例。开胸手术与开颅手术的间隔时间为18天至5年。无手术死亡病例。6例患者存活超过1年。与其他治疗方法相比,肺癌脑转移的手术治疗方法已被证明效果更好。显然,术后辅助治疗可能在提高生存率方面发挥重要作用。先进行开颅手术还是开胸手术取决于是否存在危及生命的神经症状。如果患者情况允许,应尽快进行第二次手术。需要强调的是,对于肺癌患者,应定期进行术前和术后脑部常规CT扫描,以便早期发现脑转移。同时,及时、有计划、分阶段的手术可能会提高生存率。