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MC1R 基因的错义 SNP 与游隼（Falco rusticolus）羽色变化有关。

Missense SNP of the MC1R gene is associated with plumage variation in the Gyrfalcon (Falco rusticolus).

机构信息

Organisms and Environment Division, Cardiff School of Biosciences, Cardiff University, UK.

出版信息

Anim Genet. 2012 Aug;43(4):460-2. doi: 10.1111/j.1365-2052.2011.02263.x. Epub 2011 Oct 10.

DOI:10.1111/j.1365-2052.2011.02263.x
PMID:22497627
Abstract

A single nucleotide polymorphism (MC1R: c.376A>G) in the MC1R gene was found to be highly correlated with pigment phenotype in the Gyrfalcon. Homozygous genotypes c.376GG and c.376AA were found to dominate the extreme white and dark plumage types respectively, and heterozygotes occurred mainly in intermediate phenotypes. However, some heterozygotes were associated with extreme phenotypes, indicating that melanism/albinism might also involve other loci.

摘要

在猎隼中发现了一个 MC1R 基因中的单核苷酸多态性（MC1R:c.376A>G），与色素表型高度相关。纯合基因型 c.376GG 和 c.376AA 分别主导极白和深褐色羽色类型，而杂合子主要出现在中间表型中。然而，一些杂合子与极端表型相关，表明黑化/白化也可能涉及其他基因座。

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