Lalevée Claire, Brembilla-Perrot Béatrice
Cardiology CHU of Brabois, Vandoeuvre les Nancy, France.
Cardiology CHU of Brabois, Vandoeuvre les Nancy, France.
J Electrocardiol. 2012 Jul-Aug;45(4):398-403. doi: 10.1016/j.jelectrocard.2012.03.002. Epub 2012 Apr 10.
The purpose of the study is to report the natural changes of preexcitation syndrome (PS).
Electrophysiologic study was performed for syncope (n = 8), atrioventricular reentrant tachycardia (AVRT) (n = 42), atrial fibrillation (n = 3), adverse presentation (n = 4), or for asymptomatic PS (n = 22) and was repeated 1 to 21 years later.
Clinically, 12 patients initially asymptomatic became symptomatic (54.5%), and 12 symptomatic patients became asymptomatic (21%). At electrophysiologic study 2, maximal rate conducted over accessory pathway (AP) was slower. Anterograde conduction disappeared in 22 patients, but 10 of them had inducible AVRT. Among 27 patients with initially rapid conduction over AP, 7 had a benign form; 20 had always a rapid conduction over AP, and 3 of them initially asymptomatic developed rapid atrial fibrillation.
Asymptomatic patients with a PS frequently became symptomatic (54.5%), whereas symptomatic patients rarely became asymptomatic (21%). Maximal rate conducted over AP decreased during life, but AVRT remained inducible.
本研究的目的是报告预激综合征(PS)的自然变化情况。
对晕厥患者(n = 8)、房室折返性心动过速(AVRT)患者(n = 42)、心房颤动患者(n = 3)、不良表现患者(n = 4)或无症状预激综合征患者(n = 22)进行电生理研究,并在1至21年后重复进行。
临床上,12例最初无症状的患者出现了症状(54.5%),12例有症状的患者变得无症状(21%)。在第二次电生理研究中,经旁路(AP)传导的最大速率较慢。22例患者的前传传导消失,但其中10例可诱发AVRT。在27例最初经AP快速传导的患者中,7例为良性形式;20例始终经AP快速传导,其中3例最初无症状的患者发展为快速心房颤动。
无症状预激综合征患者常出现症状(54.5%),而有症状的患者很少变为无症状(21%)。一生中经AP传导的最大速率下降,但AVRT仍可诱发。