结合连续波多普勒和类Windkessel模型中的参数估计来评估主动脉瓣反流的反流容积和瓣口面积。

Estimation of regurgitant volume and orifice in aortic regurgitation combining CW Doppler and parameter estimation in a Windkessel-like model.

作者信息

Angelsen B A, Slørdahl S A, Solbakken J E, Samstad S O, Linker D T, Torp H, Piene H

机构信息

Department of Biomedical Engineering, University of Trondheim, Norway.

出版信息

IEEE Trans Biomed Eng. 1990 Oct;37(10):930-6. doi: 10.1109/10.102805.

DOI:10.1109/10.102805

PMID:2249865

Abstract

A method for noninvasive estimation of regurgitant orifice and volume in aortic regurgitation is proposed and tested in anesthetized open chested pigs. The method can be used with noninvasive measurement of regurgitant jet velocity with continuous wave ultrasound Doppler measurements together with cuff measurements of systolic and diastolic systemic pressure in the arm. These measurements are then used for parameter estimation in a Windkessel-like model which include the regurgitant orifice as a parameter. The aortic volume compliance and the peripheral resistance are also included as parameters measurements in the open chest pigs are used. Electromagnetic flow measurements in the ascending aorta and pulmonary artery are used for control, and a correlation between regurgitant volume obtained from parameter estimation and electromagnetic flow measurements of 0.95 over a range from 2.1 to 17.8 mL is obtained.

摘要

本文提出了一种用于无创估计主动脉瓣反流瓣口面积和反流容积的方法，并在麻醉开胸猪身上进行了测试。该方法可结合连续波超声多普勒测量反流射流速度以及臂部袖带测量收缩期和舒张期体循环压力进行无创测量。然后，将这些测量值用于类似Windkessel模型的参数估计，该模型将反流瓣口面积作为一个参数。主动脉容积顺应性和外周阻力也作为参数包含在内，使用的是开胸猪的测量值。升主动脉和肺动脉的电磁流量测量用于对照，在2.1至17.8 mL的范围内，通过参数估计获得的反流容积与电磁流量测量之间的相关性为0.95。