Division of Neonatology, Department of Pediatrics, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, Taiwan.
J Microbiol Immunol Infect. 2013 Apr;46(2):136-8. doi: 10.1016/j.jmii.2012.01.015. Epub 2012 Apr 12.
A 30-day-old, previously healthy, near-term neonate presented with fever and swelling of the left eye. Orbital cellulitis of the left eye was diagnosed by computed tomography. Both blood culture and pus that was drained from the orbital abscess were positive for methicillin-resistant Staphylococcus aureus (MRSA), which was found to be a strain indigenous to the local community by a molecular method. Using vancomycin therapy and surgical drainage, the infant recovered uneventfully. Orbital cellulitis in neonates may rapidly progress to abscess formation, even to sepsis, and S. aureus is the most common pathogen. With the increasing prevalence of community-associated MRSA, empiric antibiotics effective against MRSA should be first considered in endemic areas.
一个 30 天大、之前健康的早产儿出现左眼发热和肿胀。通过计算机断层扫描诊断为左眼眶蜂窝织炎。血培养和从眼眶脓肿引流的脓液均对耐甲氧西林金黄色葡萄球菌（MRSA）呈阳性，通过分子方法发现该菌是当地社区的一株定植菌。婴儿使用万古霉素治疗和手术引流后顺利康复。新生儿眶蜂窝织炎可能迅速发展为脓肿形成，甚至脓毒症，金黄色葡萄球菌是最常见的病原体。随着社区相关耐甲氧西林金黄色葡萄球菌（CA-MRSA）的患病率不断增加，在流行地区应首先考虑使用对 CA-MRSA 有效的经验性抗生素。
