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肯尼亚三个地区四个诊所分离的淋病奈瑟菌中氟喹诺酮耐药的出现。

Emergence of fluoroquinolone resistance in Neisseria gonorrhoeae isolates from four clinics in three regions of Kenya.

机构信息

University of Manitoba, Faculty of Medicine, Department of Medical Microbiology and Infectious Diseases, Winnipeg, MB, Canada.

出版信息

Sex Transm Dis. 2012 May;39(5):332-4. doi: 10.1097/OLQ.0b013e318248a85f.

DOI:10.1097/OLQ.0b013e318248a85f
PMID:22504591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3328140/
Abstract

We have recently reported high levels of fluoroquinolone resistance in a single region of Kenya. In this article, we report high prevalence of fluoroquinolone resistance (53.2%) in Neisseria gonorrhoeae isolates from 4 clinics in 3 additional regions of Kenya. These findings highlight the need to change first-line treatment in these settings and the need to evaluate empirical management guidelines for treatment of gonococcal infection in Kenya.

摘要

我们最近报道了肯尼亚单一地区氟喹诺酮类药物耐药率很高。在本文中，我们报告了肯尼亚另外三个地区的 4 家诊所分离的淋病奈瑟菌中氟喹诺酮类药物耐药率（53.2%）很高。这些发现强调了需要在这些环境中改变一线治疗方法，并需要评估肯尼亚淋病感染经验性治疗管理指南。

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本文引用的文献

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Emergence of quinolone resistance and cephalosporin MIC creep in Neisseria gonorrhoeae isolates from a cohort of young men in Kisumu, Kenya, 2002 to 2009.2002 年至 2009 年期间，肯尼亚基苏木的一组年轻男性淋病奈瑟菌分离株中出现了喹诺酮类药物耐药和头孢菌素 MIC 攀升现象。
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High prevalence of quinolone resistance in Neisseria gonorrhoeae in coastal Kenya.肯尼亚沿海地区淋病奈瑟菌对喹诺酮耐药性的高流行率。
Sex Transm Infect. 2011 Apr;87(3):231. doi: 10.1136/sti.2010.048777. Epub 2011 Feb 9.
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Ceftriaxone-resistant Neisseria gonorrhoeae, Japan.日本的耐头孢曲松淋病奈瑟菌
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Sexually transmitted diseases treatment guidelines, 2010.性传播疾病治疗指南，2010 年。
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Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods.通过分子微生物学方法证实的两例头孢曲松治疗咽淋病失败的病例。
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Escalation in the relative prevalence of ciprofloxacin-resistant gonorrhoea among men with urethral discharge in two South African cities: association with HIV seropositivity.南非两个城市尿道分泌物男性中耐环丙沙星淋病相对患病率的上升：与HIV血清阳性的关联
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