联苯双加氧产物的双氧化。
Dioxygenation of the biphenyl dioxygenation product.
机构信息
Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
出版信息
Appl Environ Microbiol. 2012 Jun;78(12):4529-32. doi: 10.1128/AEM.00492-12. Epub 2012 Apr 13.
Abstract
Two biphenyl dioxygenases (BphAs) were shown to catalyze dioxygenation of biphenyldienediol in the nonoxidized ring to form the respective symmetrical biphenyl-bis-dienediol. This novel metabolite served as a growth substrate for both BphA source strains. Its catabolism through the upper bph pathway of Burkholderia xenovorans LB400 was analyzed.
摘要
两种联苯双加氧酶（BphAs）被证明能够催化未氧化环中联苯二烯二醇的双加氧，形成相应的对称联苯-双-二烯二醇。这种新型代谢物可作为两种 BphA 来源菌株的生长基质。通过 Burkholderia xenovorans LB400 的上 bph 途径对其进行了分析。
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