单绒毛膜双羊膜囊双胎与双绒毛膜双胎的死产前瞻性风险。

Prospective risk of stillbirth: monochorionic diamniotic twins vs. dichorionic twins.

机构信息

Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

出版信息

J Perinat Med. 2012 Jan 10;40(3):245-9. doi: 10.1515/jpm-2011-0205.

DOI:10.1515/jpm-2011-0205

PMID:22505501

Abstract

AIMS

To determine reliably the risk of stillbirth among twin pregnancies.

METHODS

A data analysis of 3241 and 6581 women with monochorionic diamniotic (MD) and dichorionic (DD) twins, respectively, who gave birth at ≥22 weeks of gestation.

RESULTS

The prospective risk (per 1000 women) of stillbirth, 25.3 and 11.5 at gestational week 22, decreased to <10.0 at gestational weeks 31 and 28 among the MD and DD twins, respectively. After single intrauterine fetal death, the co-twin died in utero or within 7 days of life more frequently among MD twins than among DD twins [42.7% (35/82) vs. 2.6% (2/76); relative risk, 16.2; 95% confidence interval, 4.0-65.1].

CONCLUSION

Women with MD twins were 2.2-fold more likely to experience stillbirth than women with DD twins. The prospective risks of stillbirth were <1.0% for both groups of women at ≥32 weeks of gestation.

摘要

目的

可靠地确定双胎妊娠中死胎的风险。

方法

对分别在妊娠 22 周及以上分娩的 3241 名和 6581 名单绒毛膜双羊膜囊（MD）和双绒毛膜双胎（DD）孕妇进行数据分析。

结果

MD 和 DD 双胎妊娠 22 周时的前瞻性风险（每 1000 名妇女）分别为 25.3 和 11.5，分别降至 31 周和 28 周时<10.0。在宫内单一胎儿死亡后，MD 双胞胎中胎儿在宫内或出生后 7 天内死亡的比例高于 DD 双胞胎[42.7%（35/82）比 2.6%（2/76）；相对风险，16.2；95%置信区间，4.0-65.1]。