Simões Teresinha, Amaral Njila, Lerman Rita, Ribeiro Filipa, Dias Elsa, Blickstein Isaac
Department of Maternal-Fetal Medicine Maternity Dr Alfredo da Costa, Lisbon, Portugal.
Am J Obstet Gynecol. 2006 Jul;195(1):134-9. doi: 10.1016/j.ajog.2006.01.099. Epub 2006 Apr 27.
The purpose of this study was to calculate the prospective risk of fetal death in monochorionic-diamniotic twins.
We evaluated 193 monochorionic diamniotic twin pregnancies that were followed and delivered after 24 weeks. Surveillance included cardiotocography and sonography performed at least once weekly. The prospective risk of fetal death was calculated as the total number of deaths at the beginning of the gestational period divided by the number of continuing pregnancies at or beyond that period.
The fetal death rate was 5 of 193 pregnancies (2.6%; 95% CI, 1.1, 5.9); the prospective risk of stillbirth per pregnancy after 32 weeks of gestation was 1.2% (95% CI, 0.3% - 4.2%).
Under intensive surveillance, the prospective risk of fetal death in monochorionic-diamniotic pregnancies after 32 weeks of gestation is much lower than reported and does not support a policy of elective preterm delivery.
本研究旨在计算单绒毛膜双羊膜囊双胎妊娠胎儿死亡的前瞻性风险。
我们评估了193例单绒毛膜双羊膜囊双胎妊娠,这些妊娠在24周后进行随访并分娩。监测包括每周至少进行一次的胎心监护和超声检查。胎儿死亡的前瞻性风险计算为妊娠期开始时的死亡总数除以该时期及以后继续妊娠的数量。
193例妊娠中有5例胎儿死亡(2.6%;95%可信区间,1.1,5.9);妊娠32周后每例妊娠死产的前瞻性风险为1.2%(95%可信区间,0.3%-4.2%)。
在强化监测下,妊娠32周后单绒毛膜双羊膜囊妊娠胎儿死亡的前瞻性风险远低于报道的风险,不支持选择性早产的政策。